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毛细血管再充盈时间测量方法及临床意义的研究进展

Research Progress on the Measurement Methods and Clinical Significance of Capillary Refill Time.

作者信息

Xia Yuxiang, Guo Zhe, Wang Xinrui, Wang Ziyi, Wang Xuesong, Wang Zhong

机构信息

School of Clinical Medicine, Tsinghua University, 30 Shuangqing Road, Haidian District Beijing, Beijing 102218, China.

Beijing Tsinghua Changgung Hospital Affiliated to Tsinghua University, 168 Litang Road, Changping District, Beijing 102218, China.

出版信息

Sensors (Basel). 2024 Dec 12;24(24):7941. doi: 10.3390/s24247941.

DOI:10.3390/s24247941
PMID:39771680
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11679391/
Abstract

The monitoring of peripheral circulation, as indicated by the capillary refill time, is a sensitive and accurate method of assessing the microcirculatory status of the body. It is a widely used tool for the evaluation of critically ill patients, the guidance of therapeutic interventions, and the assessment of prognosis. In recent years, there has been a growing emphasis on microcirculation monitoring which has led to an increased focus on capillary refill time. The International Sepsis Guidelines, the American Academy of Pediatrics, the World Health Organization, and the American Heart Association all recommend its inclusion in the evaluation of the system in question. Furthermore, the methodology for its measurement has evolved from a traditional manual approach to semiautomatic and fully automatic techniques. This article presents a comprehensive overview of the current research on the measurement of capillary refill time, with a particular focus on its clinical significance. The aim is to provide a valuable reference for clinicians and researchers and further advance the development and application of microcirculation monitoring technology.

摘要

通过毛细血管再充盈时间来监测外周循环,是评估身体微循环状态的一种灵敏且准确的方法。它是一种广泛用于评估危重症患者、指导治疗干预以及评估预后的工具。近年来,对微循环监测的重视日益增加,这使得对毛细血管再充盈时间的关注度也随之提高。国际脓毒症指南、美国儿科学会、世界卫生组织以及美国心脏协会均建议将其纳入相关系统的评估之中。此外,其测量方法已从传统的手动方式发展为半自动和全自动技术。本文全面概述了当前关于毛细血管再充盈时间测量的研究,尤其关注其临床意义。目的是为临床医生和研究人员提供有价值的参考,并进一步推动微循环监测技术的发展与应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/4a22fb3d3ada/sensors-24-07941-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/45296a6d35a3/sensors-24-07941-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/44d9713d7a18/sensors-24-07941-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/fe290e052b2b/sensors-24-07941-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/4a22fb3d3ada/sensors-24-07941-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/45296a6d35a3/sensors-24-07941-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/44d9713d7a18/sensors-24-07941-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/fe290e052b2b/sensors-24-07941-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc48/11679391/4a22fb3d3ada/sensors-24-07941-g004.jpg

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J Biomech Eng. 2025 Feb 1;147(2). doi: 10.1115/1.4067209.
2
2024 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Pediatric Life Support; Neonatal Life Support; Education, Implementation, and Teams; and First Aid Task Forces.《2024年心肺复苏与心血管急救科学及治疗建议国际共识:基础生命支持、高级生命支持、儿科生命支持、新生儿生命支持、教育、实施与团队以及急救特别工作组总结》
Resuscitation. 2024 Dec;205:110414. doi: 10.1016/j.resuscitation.2024.110414. Epub 2024 Nov 14.
3
Application of microcirculatory indicators in predicting the prognosis of patients with septic shock.微循环指标在预测感染性休克患者预后中的应用。
Heliyon. 2024 Sep 19;10(21):e38035. doi: 10.1016/j.heliyon.2024.e38035. eCollection 2024 Nov 15.
4
Quantitative Evaluation of Microcirculatory Alterations in Patients with COVID-19 and Bacterial Septic Shock through Remote Photoplethysmography and Automated Capillary Refill Time Analysis.远程光体积描记术和自动毛细血管再充盈时间分析评估 COVID-19 患者和细菌性脓毒性休克的微循环改变。
Medicina (Kaunas). 2024 Oct 14;60(10):1680. doi: 10.3390/medicina60101680.
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The Effect of Repeated Capillary Refill Tests on the Cutaneous Microcirculation.反复毛细血管再充盈试验对皮肤微循环的影响。
J Biophotonics. 2024 Oct;17(10):e202400098. doi: 10.1002/jbio.202400098. Epub 2024 Sep 3.
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Clinical guideline highlights for the hospitalist: International consensus criteria for pediatric sepsis and septic shock.临床医生指南要点:小儿脓毒症和脓毒性休克的国际共识标准。
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