Darwish Omar Isam, Koch Vitali, Vogl Thomas J, Wolf Marcos, Schregel Katharina, Purushotham Arnie, Vilgrain Valérie, Paradis Valérie, Neji Radhouene, Sinkus Ralph
Research Department of Imaging Physics and Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London WC2R 2LS, UK.
MR Predevelopment, Siemens Healthineers, 91052 Erlangen, Germany.
Sensors (Basel). 2024 Dec 17;24(24):8038. doi: 10.3390/s24248038.
MR elastography is a non-invasive imaging technique that provides quantitative maps of tissue biomechanical properties, i.e., elasticity and viscosity. Currently, hepatic MR elastography is deployed in the clinic to assess liver fibrosis in MAFLD patients. In addition, research has demonstrated MR elastography's ability to non-invasively assess chronic liver disease and to characterize breast cancer lesions and brain tumors. MR elastography requires efficient mechanical wave generation and penetration, motion-sensitized MRI sequences, and MR elastography inversion algorithms to retrieve the biomechanical properties of the tissue. MR elastography promises to enable non-invasive and versatile assessment of tissue, leading to better diagnosis and staging of several clinical conditions.
磁共振弹性成像（MR elastography）是一种非侵入性成像技术，可提供组织生物力学特性（即弹性和粘性）的定量图谱。目前，肝脏磁共振弹性成像已应用于临床，用于评估非酒精性脂肪性肝病（MAFLD）患者的肝纤维化情况。此外，研究表明磁共振弹性成像能够非侵入性地评估慢性肝病，并对乳腺癌病变和脑肿瘤进行特征描述。磁共振弹性成像需要高效的机械波产生和穿透、运动敏感的磁共振成像序列以及磁共振弹性成像反演算法来获取组织的生物力学特性。磁共振弹性成像有望实现对组织的非侵入性和多功能评估，从而更好地诊断和分期多种临床病症。
