Wang Tongyu, Niu Yanlin, Jiang Jinru, Zhang Xiaoyuan, Wang Chao, Wu Yangbo, Guo Yunchang, Li Weiwei, Zhang Penghang, Liu Yuzhu, Wang Linlin, Ma Xiaochen
Beijing Center for Disease Prevention and Control, Beijing, China.
Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, China.
Foodborne Pathog Dis. 2025 Jan 8. doi: 10.1089/fpd.2024.0067.
Listeriosis is a relatively rare but severe foodborne disease, which has significant public health concern of persons with underlying conditions and pregnant women. This study aimed to estimate the morbidity, mortality, and fatality rates of listeriosis over a 10-year period and clarify the epidemiological features of the pathogen in Beijing, China, based on voluntary reporting of sentinel surveillance. A total of 228 listeriosis cases were reported with annual morbidity rate of 1.054 per million inhabitants, including 113 maternal-neonatal cases with mean annual morbidity rate of 63.401 per million live births in Beijing from 2013 to 2022.The morbidity rate increased from 0.094 to 0.868 per million inhabitants from 2013 to 2019 ( for trend = 0.003). The overall and maternal-neonatal fatality rate were 31.82% and 42.86%, respectively. Four serogroups were identified in this study, and 1/2b predominated (89 strains). We observed the morbidity rate of listeriosis increased in Beijing over the past 10 years. Maternal-neonatal cases accounted for a higher proportion than that described in other countries, considering population base and fertility policy in China, official recommendations targeting pregnant women should be actively promoted.
李斯特菌病是一种相对罕见但严重的食源性疾病，对有基础疾病的人和孕妇具有重大的公共卫生影响。本研究旨在基于哨点监测的自愿报告，估算10年间李斯特菌病的发病率、死亡率和病死率，并阐明中国北京该病原菌的流行病学特征。共报告228例李斯特菌病病例，年发病率为每百万居民1.054例，其中包括113例母婴病例，2013年至2022年北京每百万活产儿的年平均发病率为63.401例。2013年至2019年，发病率从每百万居民0.094例增至0.868例（趋势检验P = 0.003）。总体病死率和母婴病死率分别为31.82%和42.86%。本研究鉴定出四个血清群，其中1/2b血清群占主导（89株）。我们观察到北京过去10年李斯特菌病发病率上升。考虑到中国的人口基数和生育政策，母婴病例占比高于其他国家，应积极推广针对孕妇的官方建议。
