Crawford-Jennings Matthew I, Chavez Lezith D, Loessberg Emma R, Carvallo-Chaigneau Francisco R
Virginia-Maryland College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA.
J Vet Diagn Invest. 2025 Mar;37(2):345-348. doi: 10.1177/10406387241304438. Epub 2025 Jan 7.
A 9-y-old, spayed female, non-brachycephalic mixed-breed dog was presented with progressive abdominal distension and diarrhea of <24 h duration. An echocardiogram revealed nodular masses in the pericardium and myocardium, particularly near the auricles. Diagnostic and therapeutic pericardiocentesis failed to improve the dog's status, and the owner elected euthanasia. The autopsy revealed numerous nodules within the pericardium, heart base, and myocardium of the left and right ventricles. Histopathology revealed the presence of a neuroendocrine tumor, immunopositive for chromogranin A and negative for synaptophysin and calcitonin, supporting the diagnosis of aortic body tumor with intracardiac metastasis.
一只9岁已绝育的非短头型混种雌性犬，出现进行性腹部膨胀和持续时间小于24小时的腹泻。超声心动图显示心包和心肌有结节状肿块，尤其是靠近心耳处。诊断性和治疗性心包穿刺未能改善该犬的状况，主人选择实施安乐死。尸检发现心包、心脏基部以及左右心室心肌内有大量结节。组织病理学显示存在神经内分泌肿瘤，嗜铬粒蛋白A免疫阳性，突触素和降钙素免疫阴性，支持主动脉体瘤伴心内转移的诊断。
