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探索肾移植受者对新冠病毒疫苗接种的心态:一项有深刻见解的调查分析。

Exploring the mindset of kidney transplant recipients regarding COVID-19 vaccination: An insightful survey analysis.

作者信息

Pacacı Burak, Berke Ilay, Barutcu Atas Dilek, Tugcu Murat, Arikan Hakki, Asicioglu Ebru, Tuglular Serhan, Velioglu Arzu

出版信息

Clin Nephrol. 2025 Apr;103(4):268-276. doi: 10.5414/CN111530.

Abstract

BACKGROUND

Kidney transplant (KT) recipients are at risk of severe disease and high mortality from COVID-19, and vaccination offers some degree of protection. In this study, KT recipients' and controls' attitudes towards COVID-19 vaccination were examined.

MATERIALS AND METHODS

In this cross-sectional survey-based study, the willingness and hesitancy towards COVID-19 vaccines in KT recipients and a control group from the general population were assessed via questionnaire. Vaccine hesitancy was described as either not being fully vaccinated or vaccine refusal.

RESULTS

A total of 154 KT recipients and 172 controls completed the questionnaire. The rate of those who had received at least 1 dose of COVID-19 vaccine was similar in the two study groups (92.4 vs. 92.9%, p = 0.88). The proportion of those fully vaccinated against COVID-19 was significantly lower in the KT recipients (58.7 vs. 70.4% p = 0.033). Only 11 (7.1%) of the KT recipients refused the COVID-19 vaccination. There was no significant difference between the groups in terms of vaccine refusal and vaccine hesitancy rates. Concerns about vaccine-related adverse events were common in both groups (63.6 vs. 53.8%; p = 0.488).

CONCLUSION

Although participants showed a high willingness towards COVID-19 vaccination, the number of KT recipients who were fully vaccinated appears to be lower than controls. Concerns about vaccine-related adverse events were the main reason for avoiding vaccination. Healthcare personnel, particularly nephrologists and public health experts, must take a proactive role in addressing vaccine hesitancy and ensuring that patients receive the required protection against COVID-19.

摘要

背景

肾移植(KT)受者有因 COVID-19 患上重症疾病和高死亡率的风险,而接种疫苗可提供一定程度的保护。本研究调查了 KT 受者和对照组对 COVID-19 疫苗接种的态度。

材料与方法

在这项基于横断面调查的研究中,通过问卷调查评估了 KT 受者和来自普通人群的对照组对 COVID-19 疫苗的意愿和犹豫程度。疫苗犹豫被描述为未完全接种疫苗或拒绝接种疫苗。

结果

共有 154 名 KT 受者和 172 名对照组完成了问卷调查。两个研究组中至少接种 1 剂 COVID-19 疫苗的比例相似(92.4%对 92.9%,p = 0.88)。KT 受者中完全接种 COVID-19 疫苗的比例显著低于对照组(58.7%对 70.4%,p = 0.033)。只有 11 名(7.1%)KT 受者拒绝接种 COVID-19 疫苗。两组在疫苗拒绝率和疫苗犹豫率方面无显著差异。两组中对疫苗相关不良事件的担忧都很常见(63.6%对 53.8%;p = 0.488)。

结论

尽管参与者对 COVID-19 疫苗接种表现出较高意愿,但 KT 受者中完全接种疫苗的人数似乎低于对照组。对疫苗相关不良事件的担忧是避免接种疫苗的主要原因。医护人员,尤其是肾病学家和公共卫生专家,必须积极主动地解决疫苗犹豫问题,并确保患者获得针对 COVID-19 的所需保护。

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