Anderson T M, Pitt H A, Longmire W P
Ann Surg. 1985 Apr;201(4):399-406. doi: 10.1097/00000658-198504000-00001.
Review of a 26-year experience with transduodenal sphincteroplasty and sphincterotomy was undertaken (1) to analyze critically the indications for and results of these procedures and (2) to determine which preoperative factors correlate with a good or poor outcome. Of 109 patients, 78 underwent sphincteroplasty, whereas 31 had a transduodenal sphincterotomy. Surgical indications included: group 1, 53 patients with common duct stones; group 2, 28 patients with dyskinesia or stenosis of the sphincter of Oddi (without choledocholithiasis or recurrent pancreatitis); and group 3, 28 patients with recurrent pancreatitis. Three elderly group 1 patients who presented with cholangitis died after surgery (a hospital mortality of 2.7%). Seventy-nine of the 103 patients (77%) in whom follow-up was obtained achieved an excellent or good result. Results were almost identical with sphincteroplasty and sphincterotomy. Abnormal preoperative liver function tests were the only predictors of a good postoperative outcome (p less than 0.05). Group 3 patients (good results in 63%) had significantly poorer (p less than 0.05) outcome than group 1 and 2 patients. Results were worst in group 3 patients who had undergone previous abdominal or pelvic surgery (p less than 0.025) and in group 2 patients who were narcotic users (p less than 0.025). The authors conclude that transduodenal sphincteroplasty or sphincterotomy can be performed relatively safely, but caution that careful selection of patients is important when the indication for surgery is either ampullary stenosis or recurrent pancreatitis.
对十二指肠括约肌成形术和括约肌切开术26年的经验进行了回顾,目的如下:(1)严格分析这些手术的适应证和结果;(2)确定哪些术前因素与手术效果的好坏相关。109例患者中,78例行括约肌成形术,31例行十二指肠括约肌切开术。手术适应证包括:第1组,53例胆总管结石患者;第2组,28例Oddi括约肌运动障碍或狭窄患者(无胆总管结石或复发性胰腺炎);第3组,28例复发性胰腺炎患者。3例出现胆管炎的老年第1组患者术后死亡(医院死亡率为2.7%)。103例接受随访的患者中,79例(77%)取得了优异或良好的效果。括约肌成形术和括约肌切开术的结果几乎相同。术前肝功能检查异常是术后良好效果的唯一预测因素(p<0.05)。第3组患者(63%效果良好)的手术效果明显比第1组和第2组患者差(p<0.05)。既往接受过腹部或盆腔手术的第3组患者(p<0.025)以及使用麻醉剂的第2组患者(p<0.025)手术效果最差。作者得出结论,十二指肠括约肌成形术或括约肌切开术可以相对安全地进行,但提醒当手术适应证为壶腹狭窄或复发性胰腺炎时,仔细选择患者很重要。