文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

头部基底细胞癌伴[68 Ga]OncoFAP摄取强烈。

Basal Cell Carcinoma of the Head With Intense [ 68 Ga]OncoFAP Uptake.

作者信息

Ventura David, Ernst Iris, Timma Barbara, Schäfers Michael, Backhaus Philipp

机构信息

German Cyberknife-Centre, Soest.

出版信息

Clin Nucl Med. 2025 Mar 1;50(3):e182-e183. doi: 10.1097/RLU.0000000000005595. Epub 2024 Nov 26.


DOI:10.1097/RLU.0000000000005595
PMID:39774520
Abstract

A 72-year-old man with advanced locally invasive basal cell carcinoma of the forehead failed several pretreatments including surgery and radiation. MRI was not feasible because of the presence of facial implants. CT scan did not provide clear evidence of vital/avital tumor sites as a result of slow progression and previous radiation treatments. Due to limited treatment options, the patient underwent evaluation with 68 Ga-OncoFAP PET/CT for potential stereotactic body radiation therapy. We present a rare case of advanced and metastasized basal cell carcinoma with vigorous FAP (fibroblast activation protein) expression.

摘要

一名72岁男性,患有晚期局部侵袭性前额基底细胞癌,此前接受的包括手术和放疗在内的多种预处理均失败。由于面部植入物的存在,无法进行MRI检查。由于肿瘤进展缓慢以及先前接受过放疗,CT扫描未能提供有关肿瘤活性/无活性部位的明确证据。由于治疗选择有限,该患者接受了68 Ga-OncoFAP PET/CT评估,以考虑进行立体定向体部放射治疗。我们报告了一例罕见的晚期转移性基底细胞癌,其成纤维细胞活化蛋白(FAP)表达活跃。

相似文献

[1]
Basal Cell Carcinoma of the Head With Intense [ 68 Ga]OncoFAP Uptake.

Clin Nucl Med. 2025-3-1

[2]
Translational imaging of the fibroblast activation protein (FAP) using the new ligand [Ga]Ga-OncoFAP-DOTAGA.

Eur J Nucl Med Mol Imaging. 2022-5

[3]
More advantages in detecting bone and soft tissue metastases from prostate cancer using F-PSMA PET/CT.

Hell J Nucl Med. 2019

[4]
Targeting fibroblast activation protein in newly diagnosed squamous cell carcinoma of the oral cavity - initial experience and comparison to [F]FDG PET/CT and MRI.

Eur J Nucl Med Mol Imaging. 2021-11

[5]
Head-to-Head Comparison of [ Ga]Ga-FAPI-46-PET/CT and [F]F-FDG-PET/CT for Radiotherapy Planning in Head and Neck Cancer.

Mol Imaging Biol. 2022-12

[6]
Potential Efficacy of 68 Ga-Trivehexin PET/CT and Immunohistochemical Validation of αvβ6 Integrin Expression in Patients With Head and Neck Squamous Cell Carcinoma and Pancreatic Ductal Adenocarcinoma.

Clin Nucl Med. 2024-8-1

[7]
Head-to-Head Comparison of Ga-FAPI-46 and F-FDG PET/CT for Evaluation of Head and Neck Squamous Cell Carcinoma: A Single-Center Exploratory Study.

J Nucl Med. 2022-8

[8]
Locally advanced basal cell carcinoma has a distinct methylation and transcriptomic profile.

Exp Dermatol. 2016-4

[9]
Significantly Higher 68 Ga-FAPI Than 18 F-FDG Uptake by Hidradenocarcinoma of Head and Neck on PET/CT.

Clin Nucl Med. 2024-5-1

[10]
Early metabolic 18F-FDG PET/CT response of locally advanced squamous-cell carcinoma of head and neck to induction chemotherapy: A prospective pilot study.

PLoS One. 2018-8-16

引用本文的文献

[1]
Cancer-Associated Fibroblasts: Heterogeneity, Cancer Pathogenesis, and Therapeutic Targets.

MedComm (2020). 2025-7-11

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索