Ventura David, Ernst Iris, Timma Barbara, Schäfers Michael, Backhaus Philipp
German Cyberknife-Centre, Soest.
Clin Nucl Med. 2025 Mar 1;50(3):e182-e183. doi: 10.1097/RLU.0000000000005595. Epub 2024 Nov 26.
A 72-year-old man with advanced locally invasive basal cell carcinoma of the forehead failed several pretreatments including surgery and radiation. MRI was not feasible because of the presence of facial implants. CT scan did not provide clear evidence of vital/avital tumor sites as a result of slow progression and previous radiation treatments. Due to limited treatment options, the patient underwent evaluation with 68 Ga-OncoFAP PET/CT for potential stereotactic body radiation therapy. We present a rare case of advanced and metastasized basal cell carcinoma with vigorous FAP (fibroblast activation protein) expression.
一名72岁男性，患有晚期局部侵袭性前额基底细胞癌，此前接受的包括手术和放疗在内的多种预处理均失败。由于面部植入物的存在，无法进行MRI检查。由于肿瘤进展缓慢以及先前接受过放疗，CT扫描未能提供有关肿瘤活性/无活性部位的明确证据。由于治疗选择有限，该患者接受了68 Ga-OncoFAP PET/CT评估，以考虑进行立体定向体部放射治疗。我们报告了一例罕见的晚期转移性基底细胞癌，其成纤维细胞活化蛋白（FAP）表达活跃。
