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对使用动力空气净化呼吸器(PAPR)作为封锁替代方案的要求进行审查。

Examination of the requirements for powered air-purifying respirator (PAPR) utilization as an alternative to lockdown.

作者信息

Fujii Yusaku

机构信息

Gunma University, 1-5-1 Tenjin-Cho, Kiryu, 376-8515, Japan.

出版信息

Sci Rep. 2025 Jan 7;15(1):1217. doi: 10.1038/s41598-024-82348-0.

Abstract

With the emergence of COVID-19 variants and new viruses, it remains uncertain when the next pandemic will occur. A lockdown is considered the last resort to halt the spread of infection; however, it causes significant economic and social damage. Therefore, exploring less harmful alternatives during such scenarios is crucial. This study explores the feasibility of using a powered air-purifying respirator (PAPR) as an alternative to lockdowns and as a strategy for infection control. Specifically, the study examines the potential impact of the PAPR wearing rate and PAPR aerosol shielding performance on the controllability of the spread of infections. The study investigated the necessary PAPR wearing rate and aerosol shielding performance to control infections as an alternative to the lockdown, using a simple simulation under limited conditions. When using a PAPR with 100% aerosol shielding capability in air supply, only 55% of the population needs to consistently wear the PAPR to reduce the effective reproduction number from a critical level (R = 2) to a target level (R = 0.9). Furthermore, if everyone consistently wears PAPR, only 55% the reduction ratio in the probability of becoming infected by PAPR supplying air I is enough for reducing the effective reproduction number from a critical level (R = 2) to a target level (R = 0.9). This study demonstrates the potential for utilizing PAPR as an alternative to lockdowns.

摘要

随着新冠病毒变异株和新病毒的出现,下一次大流行何时发生仍不确定。封锁被认为是阻止感染传播的最后手段;然而,它会造成重大的经济和社会损害。因此,在这种情况下探索危害较小的替代方案至关重要。本研究探讨了使用动力空气净化呼吸器(PAPR)作为封锁替代方案和感染控制策略的可行性。具体而言,该研究考察了PAPR佩戴率和气溶胶屏蔽性能对感染传播可控性的潜在影响。该研究在有限条件下通过简单模拟,调查了作为封锁替代方案控制感染所需的PAPR佩戴率和气溶胶屏蔽性能。当在供气中使用具有100%气溶胶屏蔽能力的PAPR时,仅55%的人口需要持续佩戴PAPR,就能将有效繁殖数从临界水平(R = 2)降至目标水平(R = 0.9)。此外,如果每个人都持续佩戴PAPR,仅PAPR供气I导致的感染概率降低55%就足以将有效繁殖数从临界水平(R = 2)降至目标水平(R = 0.9)。本研究证明了利用PAPR作为封锁替代方案的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3833/11707360/8f75ae862092/41598_2024_82348_Fig1_HTML.jpg

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