印度儿童急性淋巴细胞白血病幸存者中的精神障碍
Psychiatric Disorders in Survivors of Pediatric Acute Lymphoblastic Leukemia in India.
作者信息
Chopra Kanwaljeet Kaur, Gupta Aditya Kumar, Meena Jagdish Prasad, Chakrabarty Biswaroop, Sagar Rajesh, Pandey R M, Seth Rachna
机构信息
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
出版信息
Indian J Pediatr. 2025 Jan 7. doi: 10.1007/s12098-024-05365-x.
OBJECTIVES
To determine the prevalence of psychiatric morbidities in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors.
METHODS
Survivors of ALL, who had completed their treatment, atleast two or more years ago and now were 6-18 y old were enrolled on the study. The Mini International Neuropsychiatric Interview (M.I.N.I. KID) screening test for psychiatric problems was applied to all. If they had screening results positive for a particular disorder then the M.I.N.I KID standard test for that particular disorder was applied. The treatment details were noted from the records.
RESULTS
Eighty-nine survivors of ALL were enrolled. Of these, 19 (21.3%) had a psychiatric diagnosis. On multivariate analysis seizures, fears, stress and hospitalizations during treatment increased the risk of adverse psychiatric outcomes in survivorship.
CONCLUSIONS
The cancer survivors can have psychiatric problems even after completion of treatment and many easily modifiable factors contribute to the same.
目的
确定小儿急性淋巴细胞白血病（ALL）幸存者中精神疾病的患病率，并识别任何风险因素。
方法
纳入至少在两年多前完成治疗且目前年龄在6至18岁的ALL幸存者进行研究。对所有人应用用于筛查精神问题的迷你国际神经精神访谈（M.I.N.I. KID）测试。如果他们某项特定障碍的筛查结果呈阳性，则应用该特定障碍的M.I.N.I KID标准测试。从记录中获取治疗细节。
结果
共纳入89名ALL幸存者。其中，19名（21.3%）有精神疾病诊断。多因素分析显示，治疗期间的癫痫发作、恐惧、压力和住院增加了幸存者出现不良精神结局的风险。
结论
癌症幸存者即使在完成治疗后仍可能有精神问题，且许多易于改变的因素会导致同样的情况。
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