Strukov A I, Tepliakov A T, Pekarskiĭ V V
Arkh Patol. 1985;47(1):11-9.
The study of the microcirculation in lung and visceral pleura biopsies from patients with rheumatic mitral stenosis showed the involvement of all parts of the microcirculatory system including intra- and extravascular alterations and changes of the vascular wall as well as its lymphatic part. As the pressure in the small circulation circle increased and arterial hypertension established enhancement of the vascular reconstruction, rheological disturbances and dyscoagulation in the pulmonary microvessels took place. All this resulted in hemodynamic and metabolic homeostasis disturbances in the pulmonary artery system and, consequently, in the establishment of lung hypertension.
对风湿性二尖瓣狭窄患者肺及脏层胸膜活检组织的微循环研究表明,微循环系统的各个部分均受累,包括血管内和血管外改变、血管壁及其淋巴部分的变化。随着小循环圈内压力升高及动脉高血压的形成,肺微血管的血管重建增强、血液流变学紊乱和凝血功能障碍发生。所有这些导致肺动脉系统的血流动力学和代谢稳态紊乱,进而导致肺动脉高压的形成。