Sørensen P S, Trojaborg W, Gjerris F, Krogsaa B
Arch Neurol. 1985 Feb;42(2):150-3. doi: 10.1001/archneur.1985.04060020064017.
Pattern reversal visual evoked potentials in 13 patients with pseudotumor cerebri were significantly delayed (99 +/- 7.3 ms [mean +/- SD]) compared with the findings in 20 normal subjects (94 +/- 2.7 ms), although only four patients had latencies outside the normal range. There was, however, a significant correlation between the intracranial pressure and the latency of visual evoked potentials. After medical treatment of the intracranial hypertension, visual evoked potential latencies decreased in patients who recovered and in whom the papilledema disappeared. In one patient with progressive visual failure, the visual evoked potentials were abnormal before disturbances of visual fields and visual acuity were evident. Repeated examinations of visual evoked potentials might be of value in patients with pseudotumor cerebri to ensure neurosurgical intervention in due time to prevent visual loss in patients with impending optic nerve atrophy.
与20名正常受试者（94±2.7毫秒）的结果相比，13例假脑瘤患者的图形翻转视觉诱发电位显著延迟（99±7.3毫秒[平均值±标准差]），尽管只有4例患者的潜伏期超出正常范围。然而，颅内压与视觉诱发电位的潜伏期之间存在显著相关性。在对颅内高压进行药物治疗后，病情恢复且视乳头水肿消失的患者，其视觉诱发电位潜伏期缩短。在1例进行性视力减退患者中，在视野和视力出现明显障碍之前，视觉诱发电位就已异常。对于假脑瘤患者，反复检查视觉诱发电位可能有助于及时进行神经外科干预，以防止即将发生视神经萎缩的患者出现视力丧失。
