A new hydrated crystalline form of -[()-(4-hy-droxy-phen-yl)methyl-idene]-1-1,2,4-triazol-3-amine and its anti-fungal activity.

The synthesis, crystal structure, Hirshfeld analysis, and anti-fungal assessment of a new monohydrated Schiff base with a triazole moiety are reported. The structural study revealed the presence of three significant hydrogen bonds (N-H⋯N, O-H⋯N, and O-H⋯O), which contribute to the cohesion of the crystal. These bonds generate two-dimensional layers parallel to the plane, built on the basis of rings with the graph-set motifs (8) and (24). The crystal structure is further consolidated by π-π inter-actions between similar rings. The anti-fungal activity of the Schiff base was evaluated against three fungi: , , and , showing significant anti-fungal activity, particularly against .