Monomicrobial Gram-Negative Necrotizing Fasciitis of the Lower Extremity.

Unlike other skin and soft tissue infections, necrotizing fasciitis (NF) is a rare and potentially life-threatening condition. It is usually caused by polymicrobial infections or monomicrobial gram-positive organisms, mainly and . Monomicrobial gram-negative () NF is a rare form of NF, primarily reported in patients with underlying comorbidities or immunocompromised states. Here, we present a novel case of monomicrobial gram-negative NF caused by in an otherwise healthy patient. This case highlights that NF cannot be solely attributed to comorbidities, and physicians should be aware that NF can occur from infection in the absence of underlying health conditions.