Zasorin N L, Yee R D, Baloh R W
Arch Ophthalmol. 1985 Jan;103(1):55-8. doi: 10.1001/archopht.1985.01050010059019.
Ophthalmoplegia, ataxia, and areflexia are present in a distinctive syndrome called Fisher's syndrome. Eye-movement recordings were used to analyze ophthalmoplegia and other eye-movement abnormalities in three patients. Disorders of supranuclear ocular motor pathways (palsy of upward gaze and internuclear ophthalmoplegia) and peripheral cranial nerve palsies could account for the ophthalmoplegia. In one patient, computed tomography demonstrated a lucency in the midbrain that could be correlated with palsy of upward gaze and bilateral internuclear ophthalmoplegia. Eye-movement abnormalities characteristic of lesions of the midline structures of the cerebellum were documented in two patients. A review of reported cases of Fisher's syndrome and brain-stem encephalitis suggested that these syndromes comprise a spectrum of a reversible, parainfectious process affecting the peripheral cranial nerves and CNS.
眼肌麻痹、共济失调和无反射见于一种名为费希尔综合征的独特综合征。使用眼动记录来分析3例患者的眼肌麻痹及其他眼动异常。核上性眼球运动通路障碍（上视麻痹和核间性眼肌麻痹）以及周围性脑神经麻痹可解释眼肌麻痹。在1例患者中，计算机断层扫描显示中脑有透亮区，这可能与上视麻痹和双侧核间性眼肌麻痹相关。在2例患者中记录到了小脑中线结构病变特征性的眼动异常。对已报道的费希尔综合征和脑干脑炎病例的回顾表明，这些综合征构成了一个影响周围性脑神经和中枢神经系统的可逆性、感染后相关过程的范围。
