Moore Sophia, Neblett Carlos, Appiah Kenneth, Thompson Rory
Division of Plastic & Reconstructive Surgery, Department of Surgery, Kingston Public Hospital, North Street, Kingston, Jamaica.
Department of Pathology, University Hospital of the West Indies, Kingston, Jamaica.
J Surg Case Rep. 2025 Jan 7;2025(1):rjae835. doi: 10.1093/jscr/rjae835. eCollection 2025 Jan.
Gestational gigantomastia (GG) is a rare and severe clinical complication of pregnancy. It is characterized by dramatic and uncontrolled growth of the breasts, often leading to physical discomfort, psychological distress and significant surgical complications. Its pathophysiology is poorly understood; management options include conservative pharmacological and surgical interventions. Pseudoangiomatous stromal hyperplasia of the breast is a very rare, incidental, and histological diagnosis seen predominantly in women aged 30-40 years old, with the management generally involving surgical excision. The authors herein discuss an unusual case of bilateral GG complicated by pseudoangiomatous stromal hyperplasia in a premenopausal Caribbean woman, which is the second reported case in this population, with the first reported by one of our authors.
妊娠期巨乳症（GG）是一种罕见且严重的妊娠临床并发症。其特征为乳房急剧且不受控制地增大，常导致身体不适、心理困扰以及严重的手术并发症。其病理生理学尚不清楚；治疗选择包括保守的药物治疗和手术干预。乳腺假血管瘤样间质增生是一种非常罕见的、偶然发现的组织学诊断，主要见于30 - 40岁的女性，治疗通常包括手术切除。本文作者讨论了一例绝经前加勒比地区女性双侧GG合并假血管瘤样间质增生的罕见病例，这是该人群中报道的第二例，第一例由本文作者之一报道。
