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术前影像学检查实现多原发性神经内分泌肿瘤的根治性切除:一例报告

Curative resection of multiple primary neuroendocrine tumors enabled by preoperative imaging: a case report.

作者信息

Shidahara Hidetoshi, Hashimoto Masakazu, Mori Keiichi, Kuroda Shintaro, Tahara Hiroyuki, Kobayashi Tsuyoshi, Ohdan Hideki

机构信息

Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.

Department of Surgery, Yoshida General Hospital, 3666 Yoshida, Akitakata, Hiroshima 731-0595, Japan.

出版信息

J Surg Case Rep. 2025 Jan 7;2025(1):rjae805. doi: 10.1093/jscr/rjae805. eCollection 2025 Jan.

Abstract

Neuroendocrine tumors (NENs) originate from neuroendocrine cells and predominantly occur in the gastrointestinal tract, lungs, and pancreas. Although the liver is commonly involved in NEN metastasis, primary hepatic neuroendocrine tumors (PHNETs) are rare. Herein, we report a case of a 52-year-old female who presented with slowly enlarging, cystic, multiple PHNETs. Two tumors in segments 6 (S6) and S7 were noted on computed tomography (CT), and an additional S7/8 tumor was found on magnetic resonance imaging. Additionally, CT during hepatic arteriography (CTHA) revealed a small tumor in S8. No other primary tumors were detected in other organs. Posterior segmentectomy and S8 partial resection were performed for the tumors. The postoperative pathological diagnosis was a grade 2 neuroendocrine tumor. The patient showed no recurrence of tumor 3 years postoperatively. In this study, CTHA was more effective than other examinations in detecting small tumors, which could be resected without any residual tumors.

摘要

神经内分泌肿瘤(NENs)起源于神经内分泌细胞,主要发生在胃肠道、肺和胰腺。虽然肝脏常参与NEN转移,但原发性肝神经内分泌肿瘤(PHNETs)很少见。在此,我们报告一例52岁女性患者,其表现为缓慢增大的囊性多发性PHNETs。计算机断层扫描(CT)发现肝段6(S6)和S7有两个肿瘤,磁共振成像发现肝段7/8还有一个肿瘤。此外,肝动脉造影CT(CTHA)显示肝段8有一个小肿瘤。其他器官未检测到其他原发性肿瘤。对这些肿瘤进行了肝段切除术和肝段8部分切除术。术后病理诊断为2级神经内分泌肿瘤。患者术后3年未出现肿瘤复发。在本研究中,CTHA在检测小肿瘤方面比其他检查更有效,这些小肿瘤可以切除且无任何残留肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8801/11706000/f08410af0f61/rjae805f1.jpg

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