Fuentes-Sánchez Jorge, Pena-Burgos Eva Manuela, Tapia-Viñe Mar, Pozo-Kreilinger Jose Juan, Ortiz-Cruz Eduardo Jose
Orthopedic Oncologist Unit, La Paz University Hospital, P° Castellana 261, 28046 Madrid, Spain.
Pathology Department, Príncipe de Asturias University Hospital, Av. Principal de la Universidad, 1, 28805 Alcalá de Henares, Madrid, Spain.
J Surg Case Rep. 2025 Jan 7;2025(1):rjae022. doi: 10.1093/jscr/rjae022. eCollection 2025 Jan.
Angiosarcomas are a type of malignant tumor of vascular origin. They represent <1% of all primary bone tumors. The multicentric or metastatic does not differ in its high aggressiveness and poor prognosis. A 72-year-old male with bone angiosarcoma initially located in proximal femur. After biopsy in a non-expert sarcoma center, he presented tumor involvement in the needle trajectory and multicentric/metastatic involvement at the sacro-coccygeal level. He associated tumoral-hypercalcemia and was referred to our sarcoma center. He was treated by tumoral resection and tumor prosthesis. In the follow-up he presented pulmonary metastasis and new implants, dying 2 months later. Multicentric or metastatic bone involvement in angiosarcomas has only theoretical relevance for their management. Biopsy should be performed in sarcoma centers due to the risk of dissemination. Although hypercalcemia in sarcomas is uncommon, we highlight its investigation.
血管肉瘤是一种起源于血管的恶性肿瘤。它们占所有原发性骨肿瘤的比例不到1%。多中心型或转移型血管肉瘤在侵袭性和预后方面并无差异。一名72岁男性，最初诊断为股骨近端骨血管肉瘤。在一家非专业肉瘤中心进行活检后，他出现了穿刺路径上的肿瘤累及以及骶尾水平的多中心/转移累及。他伴有肿瘤性高钙血症，随后被转诊至我们的肉瘤中心。他接受了肿瘤切除和肿瘤假体植入治疗。在随访过程中，他出现了肺转移和新的植入灶，两个月后死亡。血管肉瘤的多中心或转移型骨累及在其治疗方面仅具有理论意义。由于存在播散风险，活检应在肉瘤中心进行。虽然肉瘤中的高钙血症并不常见，但我们强调对其进行检查。
