Kalaman Clarisse Roswini, Ibrahim Norhayati, Cham Choy Qing, Ho Meng Chuan, Visvalingam Uma, Abdul Rahman Fairuz Nazri, Shahabuddin Farah Ahmad, Halim Mohd Radzi Tarmizi A, Siau Ching Sin
Center for Healthy Ageing and Wellness (H-CARE), Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Institute of Islam Hadhari, Universiti Kebangsaan Malaysia, Bangi, Malaysia.
Glob Ment Health (Camb). 2024 Dec 2;11:e117. doi: 10.1017/gmh.2024.80. eCollection 2024.
Despite significant advancements in the development of psychotropic medications, increasing adherence rates remain a challenge in the treatment and management of psychiatric disorders. The purpose of this study is to qualitatively explore the challenges underlying medication adherence and strategies to improve it among adolescents with psychiatric disorders in Malaysia. This qualitative research design presents results from 17 semi-structured interviews with adolescent psychiatric patients, aged 11 to 19 years old, from public hospitals across Peninsular Malaysia. The data collected from interviews were transcribed and processed through thematic analysis using the NVivo 11 software. A total of three main themes concerning medication adherence were identified: (1) challenges; (2) coping strategies and (3) protective factors. In this study, thirteen subthemes emerge as challenges underlying medication adherence experienced by adolescent psychiatric patients. The coping strategies identified in this study fall under three broad subthemes which are problem-focused strategies, emotion-focused strategies and maladaptive strategies. This study also highlights social support and positive medicinal effects as protective factors for non-adherence issues in adolescent psychiatric patients. In conclusion, this study supports the notion that adherence is a multi-factorial phenomenon. This study can inform future development of interventions and targeted health promotion programmes in enhancing adherence.
尽管精神药物的研发取得了重大进展，但提高依从率仍是精神疾病治疗和管理中的一项挑战。本研究的目的是定性探索马来西亚患有精神疾病的青少年在药物依从性方面存在的潜在挑战以及改善依从性的策略。这种定性研究设计展示了对马来西亚半岛公立医院中11至19岁青少年精神科患者进行的17次半结构化访谈的结果。从访谈中收集的数据经过转录，并使用NVivo 11软件通过主题分析进行处理。总共确定了与药物依从性有关的三个主要主题：（1）挑战；（2）应对策略；（3）保护因素。在本研究中，出现了13个作为青少年精神科患者药物依从性潜在挑战的子主题。本研究中确定的应对策略分为三大子主题，即问题聚焦策略、情绪聚焦策略和适应不良策略。本研究还强调社会支持和积极的药物效果是青少年精神科患者不依从问题的保护因素。总之，本研究支持依从性是一个多因素现象的观点。本研究可为未来干预措施和有针对性的健康促进项目的发展提供参考，以提高依从性。
