Tan Albert Chao Chiet, Latthe Pallavi
Department of Urogynaecology, Birmingham Women's and Children NHS Foundation Trust, Birmingham, UK.
Int Urogynecol J. 2025 Mar;36(3):575-583. doi: 10.1007/s00192-024-06032-7. Epub 2025 Jan 7.
Colposuspension has been a well-accepted surgical treatment for stress urinary incontinence (SUI) since 1961. However, there is limited research on predictors of poor outcomes in both laparoscopic colposuspension (LC) and open colposuspension (OC) procedures. This study aimed to identify predictors linked to patient-reported failure after colposuspension.
This was a retrospective cohort study of women who underwent their first colposuspension surgery. The data were collected prospectively on the British Society of Urogynaecology database. The primary outcome measure was the Patient Global Impression of Improvement (PGII) for incontinence; PGII score 3-7 was defined as failure.
A total of 3104 women (1181 in LC and 1923 in OC) were analysed. On multivariate analyses, having a cystocele stage ≥ 2 was significantly predictive of failure (OR 2.573, 95% CI 1.086-6.098; p = 0.032) in LC. In OC, previous midurethral sling (MUS) procedure (OR 1.807, 95% CI 1.169-2.795; p = 0.008) and previous prolapse surgery (OR 1.954, 95% CI 1.235-3.093; p = 0.004) independently, were significant predictors of failure. OC had higher success (better PGII) than LC (p < 0.001), whilst adverse events such as blood loss, rates of urinary retention and duration of admission (p < 0.001) were lower in LC.
Variables found to be independently significant for failed colposuspension were different in the two approaches. Previous pelvic organ prolapse surgery and/or midurethral sling appeared to be the most significant predictors for failed OC, whilst in the LC group, having a stage ≥ 2 cystocele was predictive of failure.
自1961年以来,阴道悬吊术一直是压力性尿失禁(SUI)一种广泛接受的外科治疗方法。然而,关于腹腔镜阴道悬吊术(LC)和开放式阴道悬吊术(OC)手术效果不佳的预测因素的研究有限。本研究旨在确定与患者报告的阴道悬吊术后失败相关的预测因素。
这是一项对首次接受阴道悬吊手术的女性进行的回顾性队列研究。数据前瞻性收集于英国妇科学会数据库。主要结局指标是患者对尿失禁改善的总体印象(PGII);PGII评分为3 - 7被定义为失败。
共分析了3104名女性(LC组1181名,OC组1923名)。多因素分析显示,在LC组中,膀胱膨出≥2期是失败的显著预测因素(OR 2.573,95% CI 1.086 - 6.098;p = 0.032)。在OC组中,既往接受过中段尿道吊带术(MUS)(OR 1.807,95% CI 1.169 - 2.795;p = 0.008)和既往接受过脱垂手术(OR 1.954,95% CI 1.235 - 3.093;p = 0.004)独立地是失败的显著预测因素。OC组的成功率(更好的PGII)高于LC组(p < 0.001),而LC组的不良事件如失血量、尿潴留发生率和住院时间(p < 0.001)较低。
两种手术方式中,被发现对阴道悬吊术失败具有独立显著意义的变量不同。既往盆腔器官脱垂手术和/或中段尿道吊带术似乎是OC手术失败的最重要预测因素,而在LC组中,膀胱膨出≥2期是失败的预测因素。