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肠道神经病变与肠道运动障碍

Gut Neuropathies and Intestinal Motility Disorders.

作者信息

Wattchow David A, Brookes Simon J H, Spencer Nick J, De Giorgio Roberto, Costa Marcello, Dinning Phil G

机构信息

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.

Department of Surgery, Flinders Medical Centre, Adelaide, South Australia, Australia.

出版信息

Neurogastroenterol Motil. 2025 Jan 8:e14995. doi: 10.1111/nmo.14995.

Abstract

BACKGROUND

The enteric nervous system plays a key role in the coordination of gastrointestinal motility together with sympathetic, parasympathetic, and extrinsic sensory pathways. In some cases, abnormalities in neural activity in these pathways contribute to disorders of gut motility. Where this is associated with damage or death of enteric neurons, usually detected by microscopy, this is considered a gut neuropathy.

PURPOSE

This review summarizes recent advances in the identification of neuropathies in a range of gastrointestinal motility disorders.

摘要

背景

肠神经系统在协调胃肠蠕动以及交感神经、副交感神经和外在感觉通路中发挥关键作用。在某些情况下,这些通路中神经活动的异常会导致肠道蠕动障碍。若这与肠神经元的损伤或死亡相关(通常通过显微镜检测),则被视为肠道神经病变。

目的

本综述总结了在一系列胃肠蠕动障碍中神经病变识别方面的最新进展。

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