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自体牙移植保存牙槽嵴:36例连续手术的组织形态计量学分析

Alveolar ridge preservation with autogenous tooth graft: A histomorphometric analysis of 36 consecutive procedures.

作者信息

Beca-Campoy Tomás, Sánchez-Labrador Luis, Blanco-Antona Leticia Alejandra, Cortés-Bretón Brinkmann Jorge, Martínez-González José María

机构信息

Department of Surgery, Biomedical Research Institute, University of Salamanca, Spain.

Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, Spain.

出版信息

Ann Anat. 2025 Feb;258:152375. doi: 10.1016/j.aanat.2025.152375. Epub 2025 Jan 6.

Abstract

BACKGROUND

The aim of this study was to analyze the histomorphometric findings of autogenous tooth grafting (ATG) for alveolar ridge preservation (ARP), using graft material from extracted teeth. Variations by sex, age and location of extracted teeth, as well as any associated complications, were also assessed.

MATERIALS AND METHODS

This prospective, single-cohort study was conducted using ATG placed in extraction sockets. After 5 months healing, bone biopsies were collected during implant placement and analyzed histomorphometrically to assess new vital bone, residual biomaterial, and connective tissue. The results underwent statistical analysis; non-parametric tests (Mann Whitney test for independent samples and the Kruskal-Wallis test) were applied.

RESULTS

27 patients (16 females, 11 males) underwent 36 ARP procedures. Histomorphometric analysis revealed a mean percentage of new vital bone of 29.14 % ( ± 10.86), residual tooth graft of 10.84 % ( ± 6.82), and intertrabecular connective tissue of 59.87 % ( ± 10.56). No significant differences were found in relation to age, sex or location.

CONCLUSIONS

ATG appears to be a promising material for ARP, without significant complications. Further comparative studies are needed to better understand this material's behavior.

摘要

背景

本研究旨在分析使用拔除牙齿的移植材料进行自体牙移植(ATG)以保存牙槽嵴(ARP)的组织形态学结果。还评估了性别、年龄、拔除牙齿位置的差异以及任何相关并发症。

材料与方法

本前瞻性单队列研究采用将ATG植入拔牙窝。愈合5个月后,在植入种植体时采集骨活检样本,并进行组织形态学分析,以评估新生活性骨、残余生物材料和结缔组织。对结果进行统计分析;应用非参数检验(独立样本的曼-惠特尼检验和克鲁斯卡尔-沃利斯检验)。

结果

27例患者(16例女性,11例男性)接受了36次ARP手术。组织形态学分析显示,新生活性骨的平均百分比为29.14%(±10.86),残余牙移植材料为10.84%(±6.82),小梁间结缔组织为59.87%(±10.56)。在年龄、性别或位置方面未发现显著差异。

结论

ATG似乎是一种用于ARP的有前景的材料,且无明显并发症。需要进一步的比较研究以更好地了解这种材料的性能。

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