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德尔塔和早期奥密克戎时期学校重新开放与成人新冠肺炎住院率和死亡率趋势之间缺乏相关性:五个国家的生态分析

Lack of correlation between school reopening and trends in adult COVID-19 hospitalisations and death rates during the Delta and early Omicron periods: An ecological analysis of five countries.

作者信息

Ong Darren Suryawijaya, Harris Matthew, Hart John D, Russell Fiona M

机构信息

Asia-Pacific Health, Murdoch Children's Research Institute, The Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia; Department of Paediatrics, The University of Melbourne, The Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia.

Asia-Pacific Health, Murdoch Children's Research Institute, The Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia; Department of Paediatrics, The University of Melbourne, The Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia.

出版信息

J Infect. 2025 Feb;90(2):106390. doi: 10.1016/j.jinf.2024.106390. Epub 2025 Jan 6.

Abstract

OBJECTIVES

In this ecological study, we describe SARS-CoV-2 case incidence and COVID-19 hospitalisation and death rates for school-aged and adult populations during the Delta and early Omicron periods, before and after schools reopened in five countries.

METHODS

Data were extracted from government websites. Cases and COVID-19 hospitalisation and death incidence rates were calculated during the Delta and early Omicron periods in Australia, Canada, Denmark, Finland and the United Kingdom, for two weeks preceding and six weeks after schools reopened. We summarised stringency of public health measures (GRI), COVID-19 vaccination rates by age and SARS-CoV-2 testing rates.

RESULTS

During Delta, cases increased in 2/7 sites after schools reopened, hospitalisations increased in 1/5 sites, while deaths decreased in one and increased then decreased in another. During Omicron, cases increased in 2/8 sites, hospitalisations increased in 1/6 sites and deaths increased in 1/4 sites. The hospitalisation and death rate trends that commenced before schools reopened continued on the same trajectory after schools reopened. Vaccination rates in ≥70-year-olds were 75-100% during Delta and 95-100% during Omicron. Wide variations in testing rates may explain differences in case incidence. GRI were higher and more variable during Delta than during Omicron.

CONCLUSIONS

Reopening schools did not change the existing trajectory of COVID-19 rates.

摘要

目的

在这项生态学研究中,我们描述了五个国家学校重新开学前后,在德尔塔和早期奥密克戎时期学龄儿童和成人人群中新冠病毒2型病例发病率、新冠住院率和死亡率。

方法

数据从政府网站提取。计算了澳大利亚、加拿大、丹麦、芬兰和英国在德尔塔和早期奥密克戎时期,学校重新开学前两周和开学后六周的病例数、新冠住院率和死亡率。我们总结了公共卫生措施的严格程度(综合反应指数)、按年龄划分的新冠疫苗接种率和新冠病毒2型检测率。

结果

在德尔塔时期,学校重新开学后,7个地区中有2个地区病例数增加,5个地区中有1个地区住院人数增加,1个地区死亡人数减少,另1个地区死亡人数先增加后减少。在奥密克戎时期,8个地区中有2个地区病例数增加,6个地区中有1个地区住院人数增加,4个地区中有1个地区死亡人数增加。学校重新开学前开始的住院率和死亡率趋势在开学后继续保持相同轨迹。在德尔塔时期,70岁及以上人群的疫苗接种率为75%-100%,在奥密克戎时期为95%-100%。检测率的广泛差异可能解释了病例发病率的差异。与奥密克戎时期相比,德尔塔时期的综合反应指数更高且变化更大。

结论

学校重新开学并未改变新冠疫情现有趋势。

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