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来自前列腺和精囊的雄激素调节基因具有上游序列同源性。

Androgen regulated genes from prostate and seminal vesicle share upstream sequence homologies.

作者信息

Kandala J C, Kistler M K, Kistler W S

出版信息

Biochem Biophys Res Commun. 1985 Jan 31;126(2):948-52. doi: 10.1016/0006-291x(85)90277-3.

Abstract

The genes for seminal vesicle secretory protein IV and prostate steroid binding protein component 3 of the rat share upstream homologies of which the most striking is a 30 nucleotide sequence located between position -190 and -330 relative to the major transcriptional initiation sites. This sequence does not appear to be a common repetitive element and deserves consideration as a potential site involved in the androgen regulated expression of these genes.

摘要

大鼠精囊分泌蛋白IV和前列腺类固醇结合蛋白组分3的基因具有上游同源性,其中最显著的是一个30个核苷酸的序列,位于相对于主要转录起始位点的-190至-330位置之间。该序列似乎不是常见的重复元件,值得作为参与这些基因雄激素调控表达的潜在位点加以考虑。

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