[手术麻醉期间粒细胞趋化性的改变]
[Modification of granulocyte chemotaxis during anesthesia for surgery].
作者信息
Valentino M, Arcaleni R, Visonà I, Governa M
出版信息
Boll Soc Ital Biol Sper. 1985 Jan 30;61(1):145-9.
The PMNs of fourteen patients undergoing general anesthesia for surgical operations were examined to determine whether abnormal chemotaxis occurs during these procedures. Neutrophil chemotaxis was determined immediately before anesthesia and after the anesthetic somministration. Anesthetic agents included 0.2-1% enflurane, 0.3-1% halothane or N20-02 (60:40). Neutrophil chemotaxis was reduced an average of 10.9% by fluorinated anesthetics, no significant modification (+8.1 +/- 13.0%) was detected by N20-02.
对14名接受外科手术全身麻醉的患者的多形核中性粒细胞进行检查，以确定在这些手术过程中是否会出现异常趋化性。在麻醉前和给予麻醉剂后立即测定中性粒细胞趋化性。麻醉剂包括0.2 - 1%的恩氟烷、0.3 - 1%的氟烷或N20 - O2（60:40）。氟化麻醉剂使中性粒细胞趋化性平均降低10.9%，而N20 - O2未检测到显著变化（+8.1 +/- 13.0%）。
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