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一例最初疑似系统性红斑狼疮的罕见且引人关注的威尔逊病病例。

A Rare and Intriguing Case of Wilson's Disease Initially Suspected of Systemic Lupus Erythematosus.

作者信息

Khodashahi Mandana, Mohajeri Najmeh, Alipour Moeid Reza, Khademi Reza, Roshan Nama Mohamadian, Aminzadeh Behzad, Joghatayi Muhammed

机构信息

Rheumatic Diseases Research Center, Ghaem Hospital, Taghi Abad Mashhad University of Medical Sciences Mashhad Iran.

Department of Pathology, Ghaem Hospital, Taghi Abad Mashhad University of Medical Sciences Mashhad Iran.

出版信息

Clin Case Rep. 2025 Jan 7;13(1):e70091. doi: 10.1002/ccr3.70091. eCollection 2025 Jan.

Abstract

When systematic lupus erythematosus-like lab results (e.g., positive anti-double-stranded DNA antibody, low complement component 3) are inconsistent with physical findings, such as the absence of arthritis or nephritis, clinicians should consider diagnoses such as Wilson's disease, especially in the presence of abnormal liver function and elevated international normalized ratio (INR).

摘要

当系统性红斑狼疮样实验室检查结果(例如,抗双链DNA抗体阳性、补体成分3降低)与体格检查结果不一致,如无关节炎或肾炎时,临床医生应考虑诸如威尔逊病等诊断,尤其是在存在肝功能异常和国际标准化比值(INR)升高的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3039/11706692/eb645c8bfb9d/CCR3-13-e70091-g002.jpg

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