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Eggerthella lenta bacteremia successfully treated with ceftizoxime: case report and review of the literature.艰难梭菌血症成功治疗:病例报告和文献复习。
Eur J Med Res. 2021 Sep 20;26(1):111. doi: 10.1186/s40001-021-00582-y.
2
Clinical and microbiological characteristics of Eggerthella lenta bacteremia at a Japanese tertiary hospital.日本一家三甲医院的迟缓真杆菌菌血症的临床和微生物学特征。
J Infect Chemother. 2021 Aug;27(8):1261-1264. doi: 10.1016/j.jiac.2021.03.019. Epub 2021 Apr 11.
3
Antimicrobial susceptibility testing of Eggerthella lenta blood culture isolates at a university hospital in Belgium from 2004 to 2018.2004 年至 2018 年期间,比利时一所大学医院分离的迟缓埃格特菌血培养物的药敏试验。
Anaerobe. 2021 Jun;69:102348. doi: 10.1016/j.anaerobe.2021.102348. Epub 2021 Feb 14.
4
Eggerthella lenta Bloodstream Infections Are Associated With Increased Mortality Following Empiric Piperacillin-Tazobactam (TZP) Monotherapy: A Population-based Cohort Study.迟缓真杆菌血流感染与经验性哌拉西林他唑巴坦(TZP)单药治疗后死亡率增加相关:一项基于人群的队列研究。
Clin Infect Dis. 2018 Jul 2;67(2):221-228. doi: 10.1093/cid/ciy057.
5
The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections.从全球视角看腹腔内感染的管理:2017 年 WSES 腹腔内感染管理指南。
World J Emerg Surg. 2017 Jul 10;12:29. doi: 10.1186/s13017-017-0141-6. eCollection 2017.
6
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Anaerobe. 2017 Oct;47:70-72. doi: 10.1016/j.anaerobe.2017.04.010. Epub 2017 Apr 22.
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Microbiological diagnosis of Eggerthella lenta blood culture isolates in a Swedish tertiary hospital: Rapid identification and antimicrobial susceptibility profile.瑞典一家三级医院迟缓埃格特菌血培养分离株的微生物学诊断:快速鉴定及抗菌药物敏感性分析
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8
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J Clin Microbiol. 2015 Feb;53(2):626-35. doi: 10.1128/JCM.02926-14. Epub 2014 Dec 17.
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日本某大学医院5年期间感染的临床特征及抗菌药物敏感性

Clinical characteristics and antimicrobial susceptibility of infection over a 5-year trend at a university hospital in Japan.

作者信息

Mori Nobuaki, Nakamura Akiko, Hirai Jun, Asai Nobuhiro, Shibata Yuichi, Takayama Mina, Kawamoto Yuzuka, Miyazaki Narimi, Sakanashi Daisuke, Ohno Tomoko, Yamada Atsuko, Suematsu Hiroyuki, Koita Isao, Chida Sumie, Ohta Toshiaki, Mikamo Hiroshige

机构信息

Department of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Japan.

Department of Infection Prevention and Control, Aichi Medical University Hospital, Nagakute, Japan.

出版信息

Nagoya J Med Sci. 2024 Nov;86(4):683-692. doi: 10.18999/nagjms.86.4.683.

DOI:10.18999/nagjms.86.4.683
PMID:39780922
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11704767/
Abstract

() is known to cause intra-abdominal and anaerobic bloodstream infections. However, clinical insights and information on antimicrobial susceptibility in infections are limited. This study aimed to elucidate the clinical characteristics and antimicrobial susceptibility of infections. Patients with isolated from various specimens who presented at Aichi Medical University Hospital between January 2018 and December 2022 were included. Patient information was retrospectively collected from electronic medical records. Logistic regression analysis was conducted to identify risk factors for bloodstream infections. The antimicrobial susceptibility of various antimicrobial agents against isolated strains was investigated. During the study period, seventy cases were classified as infection cases. The median age of patients was 69 years (range: 15-100 years), and 48 (68.6%) were males. The most common site of infection was the lower digestive tract (54.3%). In 70.4% of cases, polymicrobial infections occurred. Community-acquired infection was a significant risk factor for bloodstream infection, with an odds ratio of 4.94 (95% confidence interval: 1.02-23.9). The 30-day mortality rate was 10.0%. Univariate analysis showed lower mortality in patients who underwent surgical intervention than in those who did not (42.9% vs 57.1%, = 0.02). The proportion of minimal inhibitory concentrations (MICs) of ≥ 32 μg/mL for piperacillin-tazobactam was 6.3%. Additionally, the proportions of MICs of ≥ 8 μg/mL for imipenem and meropenem were 1.4% and 0%, respectively. should be considered when blood cultures yield gram-positive rods in community-acquired intra-abdominal infections. Effective treatment involves both antimicrobial agents and surgical interventions.

摘要

已知(某种病菌,原文未明确)会导致腹腔内感染和厌氧性血流感染。然而,关于该病菌感染的临床见解和抗菌药敏信息有限。本研究旨在阐明该病菌感染的临床特征和抗菌药敏情况。纳入了2018年1月至2022年12月期间在爱知医科大学医院就诊、从各种标本中分离出该病菌的患者。从电子病历中回顾性收集患者信息。进行逻辑回归分析以确定血流感染的危险因素。研究了各种抗菌药物对分离菌株的抗菌药敏情况。在研究期间,70例被归类为感染病例。患者的中位年龄为69岁(范围:15 - 100岁),48例(68.