Mori Nobuaki, Nakamura Akiko, Hirai Jun, Asai Nobuhiro, Shibata Yuichi, Takayama Mina, Kawamoto Yuzuka, Miyazaki Narimi, Sakanashi Daisuke, Ohno Tomoko, Yamada Atsuko, Suematsu Hiroyuki, Koita Isao, Chida Sumie, Ohta Toshiaki, Mikamo Hiroshige
Department of Clinical Infectious Diseases, Aichi Medical University, Nagakute, Japan.
Department of Infection Prevention and Control, Aichi Medical University Hospital, Nagakute, Japan.
Nagoya J Med Sci. 2024 Nov;86(4):683-692. doi: 10.18999/nagjms.86.4.683.
() is known to cause intra-abdominal and anaerobic bloodstream infections. However, clinical insights and information on antimicrobial susceptibility in infections are limited. This study aimed to elucidate the clinical characteristics and antimicrobial susceptibility of infections. Patients with isolated from various specimens who presented at Aichi Medical University Hospital between January 2018 and December 2022 were included. Patient information was retrospectively collected from electronic medical records. Logistic regression analysis was conducted to identify risk factors for bloodstream infections. The antimicrobial susceptibility of various antimicrobial agents against isolated strains was investigated. During the study period, seventy cases were classified as infection cases. The median age of patients was 69 years (range: 15-100 years), and 48 (68.6%) were males. The most common site of infection was the lower digestive tract (54.3%). In 70.4% of cases, polymicrobial infections occurred. Community-acquired infection was a significant risk factor for bloodstream infection, with an odds ratio of 4.94 (95% confidence interval: 1.02-23.9). The 30-day mortality rate was 10.0%. Univariate analysis showed lower mortality in patients who underwent surgical intervention than in those who did not (42.9% vs 57.1%, = 0.02). The proportion of minimal inhibitory concentrations (MICs) of ≥ 32 μg/mL for piperacillin-tazobactam was 6.3%. Additionally, the proportions of MICs of ≥ 8 μg/mL for imipenem and meropenem were 1.4% and 0%, respectively. should be considered when blood cultures yield gram-positive rods in community-acquired intra-abdominal infections. Effective treatment involves both antimicrobial agents and surgical interventions.
已知(某种病菌,原文未明确)会导致腹腔内感染和厌氧性血流感染。然而,关于该病菌感染的临床见解和抗菌药敏信息有限。本研究旨在阐明该病菌感染的临床特征和抗菌药敏情况。纳入了2018年1月至2022年12月期间在爱知医科大学医院就诊、从各种标本中分离出该病菌的患者。从电子病历中回顾性收集患者信息。进行逻辑回归分析以确定血流感染的危险因素。研究了各种抗菌药物对分离菌株的抗菌药敏情况。在研究期间,70例被归类为感染病例。患者的中位年龄为69岁(范围:15 - 100岁),48例(68.