Golan A, Azem K, Gogol A, Weiss L, Gorfil D, Fein S, Orbach-Zinger S
Department of Anaesthesia Rabin Medical Centre, Beilinson Hospital Petah Tikva Israel.
Cardiothoracic Intensive Care Unit Rabin Medical Centre, Beilinson Hospital Petah Tikva Israel.
Anaesth Rep. 2025 Jan 7;13(1):e12339. doi: 10.1002/anr3.12339. eCollection 2025 Jan-Jun.
Venous thromboembolic disease remains a leading cause of maternal morbidity and mortality. We report a case of a 30-year-old woman at 37 gestation with a history of thalassaemia intermedia and splenectomy. During pregnancy, she had been managed with frequent blood transfusions and enoxaparin. She was admitted for induction of labour, and during labour, she developed pre-eclampsia with severe features. Despite magnesium sulphate therapy, she had a short self-terminating seizure shortly after an epidural had been sited. A decision to proceed with an urgent caesarean birth under epidural anaesthesia was made. After birth, she had another seizure associated with oxygen desaturation. Bag-valve-mask ventilation was insufficient, prompting conversion to general anaesthesia and tracheal intubation, after which cardiac collapse developed. Resuscitation was initiated and bedside cardiac ultrasound revealed a large clot-in-transit through the right atrium and ventricle, prompting immediate transfer to cardiac theatres for thrombectomy. The thrombus was successfully removed. The patient recovered well and her trachea was extubated the next day. She was discharged in a stable condition 8 days later. This case highlights the critical role of point-of-care ultrasound in the prompt diagnosis of life-threatening conditions and guiding emergency interventions.
静脉血栓栓塞性疾病仍然是孕产妇发病和死亡的主要原因。我们报告一例30岁女性病例,该女性妊娠37周,有中间型地中海贫血和脾切除病史。孕期,她接受了频繁输血和依诺肝素治疗。她因引产入院,分娩期间,出现了伴有严重特征的子痫前期。尽管使用了硫酸镁治疗,但在硬膜外穿刺后不久,她出现了一次短暂的自限性癫痫发作。决定在硬膜外麻醉下紧急剖宫产。产后,她又出现一次与氧饱和度下降相关的癫痫发作。球囊面罩通气不足,促使转为全身麻醉并进行气管插管,之后出现心脏骤停。立即开始复苏,床旁心脏超声显示有一个大的移动血栓通过右心房和心室,促使立即转至心脏手术室进行血栓切除术。血栓被成功取出。患者恢复良好,次日拔除气管插管。8天后她病情稳定出院。该病例凸显了床旁超声在迅速诊断危及生命的情况和指导紧急干预方面的关键作用。