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口服避孕药与严重精神疾病:无关联。

Oral contraception and serious psychiatric illness: absence of an association.

作者信息

Vessey M P, McPherson K, Lawless M, Yeates D

出版信息

Br J Psychiatry. 1985 Jan;146:45-9. doi: 10.1192/bjp.146.1.45.

DOI:10.1192/bjp.146.1.45
PMID:3978343
Abstract

The incidence of serious psychiatric illness, as measured by first referral to hospital for specialist advice and treatment, has been investigated among 16,746 women taking part in the Oxford Family Planning Association contraceptive study. Of these women, 9,504 were recruited while using oral contraceptives, 4,144 while using a diaphragm and 3,098 while using an intrauterine device. The results are reassuring with respect to oral contraceptive use. First referral rates per 1000 woman-years of observation in the oral contraceptive, diaphragm, and intrauterine device entry groups were 3.0, 2.6, and 2.8 respectively for non-psychotic psychiatric disorders and 0.46, 0.43 and 0.53 respectively for psychotic disorders. Attempted suicide occurred only 40% as often amongst diaphragm users as amongst users of oral contraceptives or intrauterine devices; this finding presumably reflects the characteristics of women who choose the diaphragm as their birth control method.

摘要

通过首次转诊至医院寻求专科建议和治疗来衡量的严重精神疾病发病率,已在参与牛津计划生育协会避孕研究的16746名女性中进行了调查。在这些女性中,9504人在使用口服避孕药时被招募,4144人在使用子宫帽时被招募,3098人在使用宫内节育器时被招募。关于口服避孕药的使用,结果令人放心。口服避孕药组、子宫帽组和宫内节育器组每1000妇女年观察期的首次转诊率,非精神病性精神障碍分别为3.0、2.6和2.8,精神病性障碍分别为0.46、0.43和0.53。子宫帽使用者的自杀未遂发生率仅为口服避孕药或宫内节育器使用者的40%;这一发现可能反映了选择子宫帽作为避孕方法的女性的特征。

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1
Oral contraception and serious psychiatric illness: absence of an association.口服避孕药与严重精神疾病:无关联。
Br J Psychiatry. 1985 Jan;146:45-9. doi: 10.1192/bjp.146.1.45.
2
Epidemiology of endometriosis in women attending family planning clinics.在计划生育诊所就诊女性的子宫内膜异位症流行病学。
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Mortality among oral contraceptive users: 20 year follow up of women in a cohort study.口服避孕药使用者的死亡率:队列研究中女性的20年随访
BMJ. 1989 Dec 16;299(6714):1487-91. doi: 10.1136/bmj.299.6714.1487.
4
Characteristics of women using different methods of contraception--some preliminary findings from a prospective study.
Int J Epidemiol. 1972 Summer;1(2):119-23. doi: 10.1093/ije/1.2.119.
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Incidence of depressive symptoms in users of the oral contraceptive.口服避孕药使用者中抑郁症状的发生率。
Br J Psychiatry. 1978 May;132:431-40. doi: 10.1192/bjp.132.5.431.
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[Vaginal and intrauterine contraception].[阴道及宫内避孕]
Rev Prat. 1995 Dec 1;45(19):2407-15.
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Oral contraceptives and breast cancer: final report of an epidemiological study.口服避孕药与乳腺癌:一项流行病学研究的最终报告。
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The Oxford-Family Planning Association contraceptive study.牛津计划生育协会避孕研究。
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Efficacy of different contraceptive methods.不同避孕方法的效果
Lancet. 1982 Apr 10;1(8276):841-2. doi: 10.1016/s0140-6736(82)91885-2.

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Women's health, hormonal balance, and personal autonomy.女性健康、激素平衡与个人自主权。
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Mortality among oral contraceptive users: 20 year follow up of women in a cohort study.
口服避孕药使用者的死亡率:队列研究中女性的20年随访
BMJ. 1989 Dec 16;299(6714):1487-91. doi: 10.1136/bmj.299.6714.1487.