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牛津计划生育协会避孕研究。

The Oxford-Family Planning Association contraceptive study.

作者信息

Vessey M P, Lawless M

出版信息

Clin Obstet Gynaecol. 1984 Dec;11(3):743-57.

PMID:6509857
Abstract

The Oxford-Family Planning Association contraceptive study involves over 17 000 women who were recruited at 17 clinics in England and Scotland during the interval 1968-74 and have been followed up ever since. This paper describes the survey methods, the characteristics of the participants, the progress of the study, the main results and publications to date, and the proposals for future work. Although the study was originally mainly concerned with the benefits and risks of oral contraceptives it has, in fact, contributed to knowledge about a wide variety of birth control methods. The data on efficacy are of special value in that they cover all methods of contraception in common use and have been derived from a homogeneous and closely observed population. The mortality figures, while limited in extent, have supplemented the findings in the Royal College of General Practitioners study. Reports on morbidity from many different diseases have been published; these have documented both beneficial and harmful effects of various contraceptive methods. The study data on return of fertility after discontinuation of contraception are unique, while contributions have also been made to knowledge about outcome of pregnancy in those stopping contraception to have a planned baby or becoming accidentally pregnant while using a birth control method. The study, which is supported by the Medical Research Council, is currently funded until mid-1989.

摘要

牛津计划生育协会的避孕研究涉及17000多名女性,她们于1968年至1974年间在英格兰和苏格兰的17家诊所招募,此后一直在接受随访。本文介绍了调查方法、参与者的特征、研究进展、主要结果和迄今发表的论文,以及对未来工作的建议。尽管该研究最初主要关注口服避孕药的益处和风险,但实际上它为了解各种避孕方法做出了贡献。疗效数据具有特殊价值,因为它们涵盖了所有常用的避孕方法,并且来自一个同质且密切观察的人群。死亡率数据虽然范围有限,但补充了皇家全科医师学院研究的结果。已经发表了关于多种不同疾病发病率的报告;这些报告记录了各种避孕方法的有益和有害影响。关于停止避孕后生育能力恢复的研究数据是独一无二的,同时也为了解那些停止避孕以生育计划内婴儿或在使用避孕方法时意外怀孕的女性的妊娠结局做出了贡献。这项由医学研究理事会支持的研究目前的资金支持到1989年年中。

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