Marchive Marion, Rossion Bruno, Lochy Aliette
University of Luxembourg.
Université de Lorraine.
J Cogn Neurosci. 2025 May 1;37(5):988-1008. doi: 10.1162/jocn_a_02286.
Fast periodic visual stimulation (FPVS) coupled with EEG has been used for a decade to measure word-selective neural responses in (a)typical adults and developmental readers. Here, we used this FPVS-EEG approach to evaluate suitable and optimal stimulation frequency rates for prelexical and lexical word-selective responses and relate these rates to typical reading speed and interindividual variability in reading performance. EEG was recorded in 41 healthy adults who viewed words inserted periodically (1 Hz) at four different stimulation frequency rates (4 Hz, 6 Hz, 10 Hz, and 20 Hz). At all these stimulation rates but the highest (20 Hz), we found typical left-lateralized, word-selective, occipitotemporal responses, larger for the prelexical (words in nonwords) than lexical (words in pseudowords) contrast. Although significant responses were found at all frequency rates, these responses were negligible at 20 Hz, without any evidence of left lateralization at this frequency. The largest occipitotemporal response was found at a 4 Hz base rate in both hemispheres for the prelexical contrast, with increased left lateralization for the lexical discrimination. Moreover, word-selective responses for this discrimination (lexical), only at 4 Hz, were related to reading speed. The optimal 4 Hz rate finding is in line with the mean reading speed for expert readers as assessed during text reading. Overall, these findings further validate and optimize the FPVS-EEG approach for rapid implicit measurement of word-selective neural responses.
快速周期性视觉刺激（FPVS）与脑电图（EEG）相结合已被用于测量（非）典型成年人及发展性阅读者的词汇选择性神经反应长达十年。在此，我们使用这种FPVS-EEG方法来评估词前和词汇词选择性反应的合适及最佳刺激频率，并将这些频率与典型阅读速度及阅读表现的个体间差异联系起来。对41名健康成年人进行脑电图记录，他们以四种不同的刺激频率（4Hz、6Hz、10Hz和20Hz）观看以1Hz周期性插入的单词。在除最高频率（20Hz）之外的所有这些刺激频率下，我们发现了典型的左侧化、词汇选择性枕颞叶反应，词前（非单词中的单词）对比比词汇（假单词中的单词）对比的反应更大。尽管在所有频率下都发现了显著反应，但这些反应在20Hz时可忽略不计，在该频率下没有任何左侧化的证据。在两个半球中，词前对比在4Hz基础频率下发现了最大的枕颞叶反应，词汇辨别时左侧化增加。此外，仅在4Hz时，这种辨别（词汇）的词汇选择性反应与阅读速度相关。最佳的4Hz频率发现与文本阅读期间评估的专家阅读者的平均阅读速度一致。总体而言，这些发现进一步验证并优化了FPVS-EEG方法，用于快速隐式测量词汇选择性神经反应。
