McDonald P T, Asman S M, Terwedow H A
Can J Genet Cytol. 1978 Dec;20(4):581-8. doi: 10.1139/g78-067.
An alternative pseudolinkage procedure for isolating homozygotes of autosomal translocations has been developed with the mosquito Culex tarsalis (Coquillet). The first step was to induce a translocation heterozygote in a population that was marked with recessive mutants. Interbred translocation heterozygotes produced translocation homozygotes that were phenotypically different from their translocation heterozygote and normal siblings. Thus, a translocation homozygote line of this species was selected and established in shorter time and with less effort than by prior pseudolinkage procedure.
已经开发出一种用于分离库蚊（Coquillet）常染色体易位纯合子的替代假连锁程序。第一步是在一个用隐性突变体标记的群体中诱导产生一个易位杂合子。相互杂交的易位杂合子产生的易位纯合子，其表型与其易位杂合子和正常同胞不同。因此，与之前的假连锁程序相比，该物种的易位纯合子系能在更短的时间内、以更少的工作量被选择和建立起来。
