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内感受觉敏感性在外阴痛中对疼痛中枢敏化的作用。

The role of interoceptive sensibility on central sensitization to pain in vulvodynia.

作者信息

Scarpina Federica, Navarra Maria Elena, Varallo Giorgia, Bernorio Roberto

机构信息

"Rita Levi Montalcini" Department of Neurosciences, University of Turin, 10126 Turin, Italy.

Istituto di Ricovero e Cura a Carattere Scientifico Istituto Auxologico Italiano, Unità Operativa di Neurologia e Neuroriabilitazione, Ospedale San Giuseppe, 28824 Piancavallo (VCO), Italy.

出版信息

J Sex Med. 2025 Apr 8;22(3):491-499. doi: 10.1093/jsxmed/qdae203.

Abstract

BACKGROUND

Interoception may be linked to central sensitization in chronic pain.

AIM

We aimed to provide evidence about the role of interoceptive sensibility on central sensitization in vulvodynia.

METHODS

In this cross-sectional study, a sample of females who received a diagnosis of vulvodynia filled out validated questionnaires relative to the individual level of interoceptive sensibility and the symptoms of central sensitization.

OUTCOMES

Interoceptive sensibility and symptoms of central sensitization were measured with the Multidimensional Assessment of Interoceptive Awareness and the Central Sensitization Inventory, respectively.

RESULTS

A lower level of trust and a higher level of emotional awareness predicted a higher number of central sensitization symptoms in our sample.

CLINICAL IMPLICATIONS

Our evidence may increase the researchers' and physicians' attention toward the involvement of the central nervous system in pain phenomenology in vulvodynia.

STRENGTHS AND LIMITATIONS

No ad-hoc control sample was collected. No behavioral assessments about interoception were performed.

CONCLUSION

As registered in other chronic pain conditions, interoceptive sensibility may play a crucial role in the expressions of symptoms of central sensitization in vulvodynia.

摘要

背景

内感受可能与慢性疼痛中的中枢敏化有关。

目的

我们旨在提供证据,证明内感受敏感性在外阴痛中枢敏化中的作用。

方法

在这项横断面研究中,一组被诊断为外阴痛的女性样本填写了关于内感受敏感性个体水平和中枢敏化症状的有效问卷。

结果

分别使用内感受觉知多维评估和中枢敏化量表对内感受敏感性和中枢敏化症状进行测量。

结果

在我们的样本中,较低的信任水平和较高的情绪觉知水平预示着更多的中枢敏化症状。

临床意义

我们的证据可能会增加研究人员和医生对中枢神经系统参与外阴痛疼痛现象学的关注。

优点和局限性

未收集专门的对照样本。未对内感受进行行为评估。

结论

正如在其他慢性疼痛情况中所记录的那样,内感受敏感性可能在外阴痛中枢敏化症状的表现中起关键作用。

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