Alfì Gaspare, Maruani Julia, Aquino Giulia, Menicucci Danilo, Palagini Laura, Gemignani Angelo, Bazin Balthazar, Clerici Emmanuelle, Stern Emilie, Geoffroy Pierre A
Department of Psychiatry and Addiction Medicine, AP-HP, GHU Paris Nord, DMU Neurosciences, Hôpital Bichat-Claude Bernard, Paris, France.
Department of Surgical, Medical and Molecular Pathology and Critical Care Medicine, Pisa, Italy.
J Sleep Res. 2025 Feb;34(1):e14320. doi: 10.1111/jsr.14320. Epub 2024 Aug 19.
This exploratory study aimed to investigate the relationship between interoceptive sensibility and quality of consciousness in individuals with insomnia disorder, in order to understand how the modulation of internal states may contribute to modifying the experience of consciousness during sleep difficulties. A total of 37 patients with insomnia disorder (mean age = 46.05 ± 18.16) and 41 healthy good sleepers (mean age = 50.2 ± 12.99) underwent a psychometric sleep and interoceptive sensibility assessment, using Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and Multidimensional Assessment of Interoceptive Awareness (MAIA). Moreover, patients with insomnia disorder also completed a quality of consciousness evaluation, using the Phenomenology of Consciousness Inventory (PCI). Patients with insomnia disorder exhibited heightened interoceptive sensibility, particularly in noticing body sensations (p < 0.0001) and emotional awareness (p = 0.032), along with diminished abilities in attention regulation (p = 0.040), not-worrying (p = 0.001), and trusting (p = 0.002). Furthermore, correlations between interoceptive sensibility and multiple aspects of the consciousness state during the insomnia night were identified. Specifically, higher emotional awareness was linked to a 2.49-fold increase in the likelihood of subjectively experiencing altered consciousness states during insomnia. The study sheds light on the relationship between interoceptive sensibility and the subjective state of consciousness during insomnia, emphasising the importance of exploring and considering interoception as part of the therapeutic process for insomnia disorder. Given the exploratory nature of the study and the increased risk of type-I error from numerous correlations, the results should be interpreted with caution. Further research is needed to validate and confirm their robustness.
这项探索性研究旨在调查失眠症患者的内感受敏感性与意识质量之间的关系，以了解内部状态的调节如何有助于在睡眠困难期间改变意识体验。共有37名失眠症患者（平均年龄=46.05±18.16）和41名睡眠良好的健康人（平均年龄=50.2±12.99）接受了心理测量睡眠和内感受敏感性评估，使用失眠严重程度指数（ISI）、匹兹堡睡眠质量指数（PSQI）和内感受意识多维评估（MAIA）。此外，失眠症患者还使用意识现象学量表（PCI）完成了意识质量评估。失眠症患者表现出更高的内感受敏感性，尤其是在注意身体感觉方面（p<0.0001）和情绪意识方面（p=0.032），同时在注意力调节（p=0.040）、不担忧（p=0.001）和信任（p=0.002）方面的能力有所下降。此外，还确定了失眠之夜内感受敏感性与意识状态多个方面之间的相关性。具体而言，更高的情绪意识与失眠期间主观体验意识状态改变的可能性增加2.49倍有关。该研究揭示了失眠期间内感受敏感性与意识主观状态之间的关系，强调了探索和考虑内感受作为失眠症治疗过程一部分的重要性。鉴于该研究的探索性质以及众多相关性导致的I型错误风险增加，结果应谨慎解释。需要进一步的研究来验证和确认其稳健性。
