Jia Dingjiacheng, Chen Shujie
Department of Gastroenterology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang Province 310058, China; Institution of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.
Institution of Gastroenterology, Zhejiang University, Hangzhou, Zhejiang Province 310058, China; Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.
Cell Host Microbe. 2025 Jan 8;33(1):6-8. doi: 10.1016/j.chom.2024.12.012.
Fungal symbionts play a key role in maintaining host homeostasis. In a recent issue of Nature, Liao et al. show that Kazachstania pintolopesii, a symbiotic fungus in mice, is shielded from the host immune system during homeostasis but induces type 2 immunity during mucus fluctuations.
真菌共生体在维持宿主内环境稳定中起关键作用。在最近一期的《自然》杂志上，廖等人表明，小鼠体内的共生真菌皮氏卡扎奇酵母在稳态期间受到宿主免疫系统的保护，但在黏液波动期间会诱导2型免疫反应。
