Wang Liwei, Zhao Gang, Sandeep Bhushan
Department of General Surgery, Chengdu Second People's Hospital, Chengdu, Sichuan 610017, PR China.
Department of Emergency Surgery, Chengdu Qingbaijiang District People's Hospital, Chengdu, Sichuan, 610300, PR China.
Curr Probl Cardiol. 2025 Mar;50(3):102981. doi: 10.1016/j.cpcardiol.2025.102981. Epub 2025 Jan 7.
The importance of central hemodynamic metrics such as Central blood pressure (CBP), which directly measure the pressure exerted by the cardiac muscle on the major arteries, offering a more direct assessment of cardiovascular workload compared to brachial blood pressure (bBP), which measures pressure against the walls of peripheral arteries. This review consolidates findings that evaluate the correlation between CBP and key markers of aortovascular disease. The growth of thoracic aortic aneurysm (TAA) is a significant component of aortovascular assessment. CBP correlates more precisely with arterial stiffness (AS), TAA growth, and cardiovascular diseases, providing a more reliable forecast of aortovascular diseases, adverse cardiovascular events (CVE), and organ damage than bBP. Integrating CBP into routine clinical practice could enhance aortovascular assessments and therapeutic strategies compared to bBP, especially by gaining a deeper understanding of aortic wave dynamics, which could fundamentally change aortovascular diagnostics and treatment. It is recommended to incorporate CBP into aortovascular and cardiovascular risk management. Further research is needed to confirm these aspects and to explore the practical implications of CBP in clinical settings.
中心血流动力学指标的重要性,如中心血压(CBP),它直接测量心肌对主要动脉施加的压力,与测量外周动脉壁压力的肱动脉血压(bBP)相比,能更直接地评估心血管负荷。本综述汇总了评估CBP与主动脉血管疾病关键标志物之间相关性的研究结果。胸主动脉瘤(TAA)的生长是主动脉血管评估的重要组成部分。CBP与动脉僵硬度(AS)、TAA生长和心血管疾病的相关性更为精确,与bBP相比,能更可靠地预测主动脉血管疾病、不良心血管事件(CVE)和器官损伤。与bBP相比,将CBP纳入常规临床实践可增强主动脉血管评估和治疗策略,特别是通过更深入地了解主动脉波动动力学,这可能从根本上改变主动脉血管的诊断和治疗。建议将CBP纳入主动脉血管和心血管风险管理。需要进一步研究来证实这些方面,并探索CBP在临床环境中的实际意义。