Panzetta G, Guerra U, D'Angelo A, Sandrini S, Terzi A, Oldrizzi L, Maiorca R
Clin Nephrol. 1985 Jan;23(1):18-25.
Total body water (TBW), extracellular water (ECW), exchangeable potassium pool (EKP), and alkali-soluble nitrogen in skeletal muscle tissue (N) were determined in 9 CAPD patients on treatment from 5 to 14 months (mean 8.6 months). The parameters were reevaluated in 6 of these patients 5 to 13 months later (mean 8.6 months). The mean value of TBW was normal and directly correlated to body weight (BW), but TBW was abnormally distributed between extracellular and intracellular space. ECW volume was significantly lower than the predicted value (12.1 +/- 1.4 versus 16.8 +/- 1.9 l) and out of proportion to TBW (34.8 +/- 3.9% versus 47.8 +/- 1.5%). The calculated intracellular water, therefore, appeared clearly hyperexpanded. The mean value of EKP was slightly reduced, but in three patients there was a 25% reduction. N content was low in 5 out of 9 patients. When the parameters were re-evaluated BW and TBW were unchanged in two subjects. A third patient showed a simultaneous increase in both BW (12.7%) and TBW (19%). TBW variations (+19%, -23%, -24%) without changes in BW were seen in three patients. The mean value of EKP was unchanged, but there was a 25% reduction in one patient. N content improved in two and worsened in one of the three patients in whom it was determined. The data suggest that cell overhydration was the distinctive feature in our CAPD patients, and that the evolution of the nutritional status was variable, since the patients could remain stable, gain or loose body fat, and probably change their lean body mass.
对9例接受持续性非卧床腹膜透析（CAPD）治疗5至14个月（平均8.6个月）的患者测定了总体水（TBW）、细胞外液（ECW）、可交换钾池（EKP）以及骨骼肌组织中的碱溶性氮（N）。其中6例患者在5至13个月后（平均8.6个月）重新评估了这些参数。TBW的平均值正常且与体重（BW）直接相关，但TBW在细胞外和细胞内空间的分布异常。ECW体积显著低于预测值（12.1±1.4升对16.8±1.9升），且与TBW不成比例（34.8±3.9%对47.8±1.5%）。因此，计算得出的细胞内水明显过度扩张。EKP的平均值略有降低，但有3例患者降低了25%。9例患者中有5例N含量较低。当重新评估这些参数时，有2例患者的BW和TBW未变。第3例患者的BW（增加12.7%）和TBW（增加19%）同时升高。3例患者出现了TBW变化（+19%、-23%、-24%）而BW未变的情况。EKP的平均值未变，但有1例患者降低了25%。在测定N含量的3例患者中，有2例改善，1例恶化。数据表明，细胞水合过度是我们CAPD患者的显著特征，而且营养状况的演变是可变的，因为患者可能保持稳定、增加或减少体脂，并且可能改变其瘦体重。
