Elster A D
Clin Orthop Relat Res. 1985 Apr(194):136-41.
The Syndrome of Inappropriate Secretion of Antidiuretic Hormone (SIADH) was found to occur in at least 5% of patients recovering from a spinal fusion operation. A retrospective review was undertaken for all patients who had had a spinal fusion in 1981. The author applied strict criteria for the diagnosis of SIADH and found that at least eight of 161 patients suffered this complication. A factor analysis revealed that SIADH was most likely to develop in patients with large spinal deformities and greater than usual intraoperative blood loss. There was no correlation with age, sex, type of fusion, or cause of spinal deformity. The diagnosis, treatment, and pathogenesis of SIADH suggest that an extensive spinal fusion operation is a previously unrecognized predisposing condition.
抗利尿激素分泌不当综合征（SIADH）在至少5%接受脊柱融合手术康复的患者中被发现。对1981年所有接受脊柱融合手术的患者进行了回顾性研究。作者应用严格的标准诊断SIADH，发现161例患者中至少有8例出现了这种并发症。因素分析显示，SIADH最有可能在脊柱畸形较大且术中失血多于平常的患者中发生。与年龄、性别、融合类型或脊柱畸形原因无关。SIADH的诊断、治疗和发病机制表明，广泛的脊柱融合手术是一种先前未被认识的诱发因素。
