Dos Santos Luana Michelly Aparecida Costa, de Oliveira Alan Maicon, Aguilar Guilherme José, Dos Santos Luiz Ricardo Albano, Costa Wilbert Dener Lemos, Donato Dantony de Castro Barros, Frade Marco Andrey Cipriani, Bollela Valdes Roberto
Department of Public Health, Ribeirão Preto Medical School, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
Intersection LTDA, Ribeirão Preto, São Paulo, Brazil.
J Med Syst. 2025 Jan 10;49(1):3. doi: 10.1007/s10916-025-02145-8.
Directly Observed Treatment (DOT) involves the administration of medication and in-person monitoring by a healthcare team alongside the patient to improve adherence to tuberculosis (TB) treatment. Implementing DOT requires healthcare professionals, transportation, time dedication, and presence at the patient's residence. Meeting all these conditions is not always possible to address the high demand of TB patients who would benefit from this supervision. Video Directly Observed Therapy (VDOT) is a telecare platform created to remotely oversee the treatment of TB patients, allowing them to daily record medication intake, as prescribed, using their cell phones, clarify doubts, and facilitate communication with the healthcare team providing support. The medication intake data is recorded and accessible to healthcare professionals who monitor adherence remotely. The investigation reported in this work was conducted in Ribeirão Preto, Brazil, from May 5, 2020, to May 4, 2023, across five healthcare units. During the study period, 26,253 medication intake videos were collected and sent from 259 patients. Regarding the outcome reported by supervisors, only 9.7% of patients had their VDOT follow-up terminated due to abandonment, while the Cure/Treatment completion rate was 57.5%. Regarding adherence to the established treatment period for TB and for each patient in their specific situation, 67% of patients completed more than 66% of the treatment. The data suggested good acceptance of the system by both patients and healthcare professionals. VDOT may be a promising tool that complements TB DOT, extending its reach to improve adherence and reduce abandonment rates.
直接观察治疗(DOT)包括医疗团队在患者身边给药并进行现场监测,以提高对结核病(TB)治疗的依从性。实施DOT需要医疗专业人员、交通、时间投入以及前往患者住所。要满足所有这些条件并非总能实现,难以应对有大量受益于这种监督的结核病患者的高需求。视频直接观察治疗(VDOT)是一个远程医疗平台,旨在远程监督结核病患者的治疗,允许他们使用手机按规定每日记录药物摄入情况、澄清疑问并促进与提供支持的医疗团队的沟通。药物摄入数据会被记录下来,供远程监测依从性的医疗专业人员使用。本研究报告的调查于2020年5月5日至2023年5月4日在巴西里贝朗普雷图的五个医疗单位进行。在研究期间,共收集并收到了259名患者发送的26,253段药物摄入视频。关于监督员报告的结果,只有9.7%的患者因放弃而终止了VDOT随访,而治愈/治疗完成率为57.5%。关于结核病既定治疗期以及每个患者具体情况的依从性,67%的患者完成了超过66%的治疗。数据表明该系统得到了患者和医疗专业人员的良好接受。VDOT可能是一种有前景的工具,可作为结核病DOT的补充,扩大其覆盖范围以提高依从性并降低放弃率。