Verlohren H J, Lohmann D, Kade R, Heilmann W, Pohl A
Dtsch Z Verdau Stoffwechselkr. 1979;39(6):284-91.
In diabetic diseases of pancreatic origin we find three typical patterns of insulin secretion. The different insulin secretion allows a clear distinction of a diabetes of the maturity onset type and of the juvenile onset type type on the one hand and of a diabetes caused by a pancreatitis on the other hand. In a pancreatitis we see the expected reduction of the exocrine function. In the so called maturity onset diabetes a slight reduction of excretory functions could be seen. These results suggest that in maturity onset diabetes only a selective defect of the beta-cells exists, while in juvenile onset diabetes a destruction or reduction of beta-cells but an intact excretory function may be assumed.
在胰腺源性糖尿病中,我们发现三种典型的胰岛素分泌模式。不同的胰岛素分泌情况一方面能清晰区分成年发病型糖尿病和青少年发病型糖尿病,另一方面能区分由胰腺炎引起的糖尿病。在胰腺炎中,我们会看到外分泌功能出现预期的降低。在所谓的成年发病型糖尿病中,可观察到排泄功能略有降低。这些结果表明,成年发病型糖尿病仅存在β细胞的选择性缺陷,而青少年发病型糖尿病可能存在β细胞的破坏或减少,但排泄功能完好。