Ruan Hongyu, Zhu Xiaoxia, Xu Suling, Wang Songting, Yang Feng, Li Guixiu, Jiang Xinyu, Zhao Keyu
Department of Dermatology, The First Affiliated Hospital of Ningbo University, 59 Liuting Street, Ningbo, Zhejiang 315010, China.
Health Science Center, Ningbo University, 818 Fenghua Road, Ningbo, Zhejiang 315211, China.
J Surg Case Rep. 2025 Jan 9;2025(1):rjae838. doi: 10.1093/jscr/rjae838. eCollection 2025 Jan.
Pseudoepitheliomatous hyperplasia (PEH) is a rare histopathological reaction. Cases of PEH have been infrequently reported, and it's even rare to appear as a postsurgical complication. This case report describes the development of multiple masses and purulent discharge around an abdominal scar following surgery for hepatocellular carcinoma, which morphologically resembles squamous cell carcinoma (SCC), though pathology revealed no signs of malignancy. The underlying mechanism of PEH has not been fully characterized. This case report may alert clinicians and pathologists to rare diseases and update the list of postoperative complications.
假上皮瘤样增生（PEH）是一种罕见的组织病理学反应。PEH病例报道较少，作为术后并发症出现则更为罕见。本病例报告描述了肝细胞癌手术后腹部瘢痕周围出现多个肿块及脓性分泌物，其形态学上类似于鳞状细胞癌（SCC），尽管病理检查未发现恶性迹象。PEH的潜在机制尚未完全明确。本病例报告可能会提醒临床医生和病理学家注意罕见疾病，并更新术后并发症的清单。
