纵隔卵黄囊瘤伴隆突下淋巴结转移灶内孤立性腺癌

Mediastinal Yolk Sac Tumor With Solitary Adenocarcinoma in Subcarinal Nodal Metastases.

作者信息

Tokuda Ryosuke, Shimomura Masanori, Okada Satoru, Ishihara Shunta, Miyagawa-Hayashino Aya, Watanabe Hiroshi, Tanaka Noriyuki, Inoue Masayoshi

机构信息

Division of Thoracic Surgery, Department of Surgery, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Department of Surgical Pathology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Ann Thorac Surg Short Rep. 2023 Sep 13;2(1):108-111. doi: 10.1016/j.atssr.2023.09.005. eCollection 2024 Mar.

DOI:10.1016/j.atssr.2023.09.005

PMID:39790263

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708738/

Abstract

Germ cell tumors with somatic-type solid malignancy are mostly attributed to the malignant transformation of teratomas. Herein, we describe the case of a 41-year-old man with mediastinal yolk sac tumor who presented with adenocarcinoma in nodal metastases. Computed tomography revealed enlarged subcarinal lymph nodes and an anterior mediastinal tumor, which was diagnosed as a yolk sac tumor by percutaneous biopsy. The remaining tumor was resected after chemotherapy. No viable cells were observed in the primary tumor; however, adenocarcinoma was detected in the subcarinal lymph nodes. Mediastinal yolk sac tumors can be associated with metastatic adenocarcinoma in locoregional lymph nodes.

摘要

伴有体细胞型实体恶性肿瘤的生殖细胞肿瘤大多归因于畸胎瘤的恶性转化。在此，我们描述了一例41岁患有纵隔卵黄囊瘤的男性病例，其在淋巴结转移中出现腺癌。计算机断层扫描显示隆突下淋巴结肿大及前纵隔肿瘤，经皮活检诊断为卵黄囊瘤。化疗后切除了残余肿瘤。在原发肿瘤中未观察到存活细胞；然而，在隆突下淋巴结中检测到腺癌。纵隔卵黄囊瘤可能与局部区域淋巴结的转移性腺癌相关。