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指导成人进行Ross手术不会影响围手术期或长期预后。

Mentoring the Ross Procedure in Adults Does Not Compromise Perioperative or Long-term Outcomes.

作者信息

Shih Emily, Squiers John J, Brinkman William T, Harrington Katherine B, Schaffer Justin M, DiMaio J Michael, Ryan William H

机构信息

Department of Cardiothoracic Surgery, The Heart Hospital Baylor Scott and White, Plano, Texas.

Baylor Scott and White Research Institute, Dallas, Texas.

出版信息

Ann Thorac Surg Short Rep. 2022 Dec 26;1(2):307-310. doi: 10.1016/j.atssr.2022.12.009. eCollection 2023 Jun.

DOI:10.1016/j.atssr.2022.12.009
PMID:39790306
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11708156/
Abstract

BACKGROUND

Recent reports that the Ross procedure restores normal life expectancy in young adults with aortic valve disease have renewed interest in this complex procedure. Because only a few centers perform a high volume of Ross procedures, there are limited data on the safety of learning and teaching the Ross procedure.

METHODS

A total of 234 consecutive adult patients at a single center underwent the Ross procedure performed by an experienced surgeon acting as the primary operator (n = 186; 1994-2021) or mentoring surgeon (n = 48; 2001-2021). Cumulative sum analysis of cardiopulmonary bypass times was performed to evaluate learning curves as primary surgeon and mentored surgeon. Kaplan-Meier analysis was used to estimate long-term survival and freedom from Ross-related reintervention.

RESULTS

Patients' mean age was 42 ± 11 years; 169 (72%) were male. Baseline demographic characteristics were similar between cohorts. Operative death occurred in 5 (2%) patients: 3 (2%) as primary surgeon and 2 (4%) as mentor ( = .28). In-hospital reoperation was required in 8 (3%) patients: 6 (3%) as primary surgeon and 2 (4%) as mentor ( = .75). Up to 10 years, there was no difference in survival between primary operator cases and mentored cases (94.4% [91.2%-97.9%]) vs 95.8% [90.3%-100%]; log-rank,  = .85).

CONCLUSIONS

Although the Ross procedure is technically complex, it can be taught to experienced aortic root surgeons without compromising short- or long-term outcomes.

摘要

背景

最近有报道称,罗斯手术可恢复患有主动脉瓣疾病的年轻成年人的正常预期寿命,这重新引发了人们对这一复杂手术的兴趣。由于只有少数几个中心进行大量的罗斯手术,关于学习和教授罗斯手术安全性的数据有限。

方法

在一个中心,共有234例连续的成年患者接受了罗斯手术,手术由一位经验丰富的外科医生作为主刀医生(n = 186;1994 - 2021年)或指导医生(n = 48;2001 - 2021年)进行。对体外循环时间进行累积和分析,以评估作为主刀医生和指导医生的学习曲线。采用Kaplan-Meier分析来估计长期生存率和免于与罗斯手术相关的再次干预的概率。

结果

患者的平均年龄为42±11岁;169例(72%)为男性。两组患者的基线人口统计学特征相似。5例(2%)患者发生手术死亡:主刀医生组3例(2%),指导医生组2例(4%)(P = 0.28)。8例(3%)患者需要进行院内再次手术:主刀医生组6例(3%),指导医生组2例(4%)(P = 0.75)。长达10年,主刀医生组病例和指导医生组病例的生存率无差异(94.4%[91.2% - 97.9%]对95.8%[90.3% - 100%];对数秩检验,P = 0.85)。

结论

尽管罗斯手术技术复杂,但可以教授给有经验的主动脉根部外科医生,而不会影响短期或长期疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bb/11708156/fa390a5f466d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bb/11708156/fa390a5f466d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2bb/11708156/fa390a5f466d/gr1.jpg

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本文引用的文献

1
Outcomes of redo operations after the Ross procedure.Ross手术后继发性手术的结果。
J Thorac Cardiovasc Surg. 2023 May;165(5):1803-1812.e2. doi: 10.1016/j.jtcvs.2022.04.023. Epub 2022 May 14.
2
Propensity-Matched Comparison of the Ross Procedure and Prosthetic Aortic Valve Replacement in Adults.成人心脏的罗斯手术与人工主动脉瓣置换的倾向匹配比较。
J Am Coll Cardiol. 2022 Mar 1;79(8):805-815. doi: 10.1016/j.jacc.2021.11.057.
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Long-term outcomes of the Ross procedure in adults.成人Ross手术的长期疗效。
Ann Cardiothorac Surg. 2021 Jul;10(4):499-508. doi: 10.21037/acs-2021-rp-fs-28.
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Reconsidering the Ross Procedure.
JAMA Cardiol. 2021 May 1;6(5):548. doi: 10.1001/jamacardio.2021.0087.
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Impact of the Learning Curve on Early Outcomes Following the Ross Procedure.
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Long-Term Outcomes of the Ross Procedure Versus Mechanical Aortic Valve Replacement: Propensity-Matched Cohort Study.Ross手术与机械主动脉瓣置换术的长期结果:倾向匹配队列研究。
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Learning minimally invasive mitral valve surgery: a cumulative sum sequential probability analysis of 3895 operations from a single high-volume center.学习微创二尖瓣手术:来自单一高容量中心的 3895 例手术的累积和序贯概率分析。
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Ann Thorac Surg. 2012 May;93(5):1477-81; discussion 1481-22. doi: 10.1016/j.athoracsur.2012.01.100. Epub 2012 Mar 30.
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