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启动罗斯项目的多模式方法的结果

Results of a Multimodal Approach for the Launch of a Ross Program.

作者信息

Ibrahim Michael E, Lawrence Kendall M, Bavaria Joseph E, Grimm Joshua, Acker Michael, El-Hamamsy Ismail, Szeto Wilson Y, Desai Nimesh

机构信息

Division of Cardiovascular Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Cardiovascular Surgery, Mount Sinai Hospital, Icahn School of Medicine at Mount Sinai, New York.

出版信息

Ann Thorac Surg Short Rep. 2022 Dec 1;1(1):210-213. doi: 10.1016/j.atssr.2022.11.015. eCollection 2023 Mar.

Abstract

BACKGROUND

There has been renewed interest in the Ross procedure in young patients with aortic valve disease. We describe the details and results of a systematic strategy to launch a new Ross program.

METHODS

Our department developed a multidisciplinary educational program that involved all practitioners involved in the care of potential Ross patients. A core group of surgeons underwent extensive hands-on technical preparation. Selection of patients was reviewed by a multidisciplinary team. Patient characteristics, operative details, and postoperative outcomes were analyzed.

RESULTS

Between March 2021 and March 2022, 22 consecutive patients underwent Ross procedure at our institution. The mean age of the patients at time of operation was 40.4 ± 10.2 years, and most patients had no medical comorbidities (12/22). The most common indication for operation was aortic stenosis (13/22), followed by mixed aortic stenosis and aortic insufficiency (7/22). There were no deaths. Postoperatively, no patient required blood transfusion or reexploration for hemorrhage. All patients were discharged home on mean hospital day 5.9 ± 1.1. On predischarge echocardiography, there was a significant reduction in mean aortic gradients preoperatively to postoperatively (49 ± 20 mm Hg vs 4 ± 1 mm Hg; < .01) without aortic insufficiency or a change in left or right ventricular function.

CONCLUSIONS

We demonstrate that with multidisciplinary education and extensive hands-on surgical preparation under proctored supervision, a Ross program can be initiated safely with excellent short-term results and perioperative risk that mimics that of conventional surgical aortic valve replacement.

摘要

背景

对于患有主动脉瓣疾病的年轻患者,罗斯手术再次引起了人们的关注。我们描述了启动一项新的罗斯手术项目的系统策略的细节和结果。

方法

我们科室制定了一项多学科教育计划,该计划涉及所有参与潜在罗斯手术患者护理的从业者。一组核心外科医生接受了广泛的实践技术准备。患者的选择由多学科团队进行审查。分析了患者特征、手术细节和术后结果。

结果

在2021年3月至2022年3月期间,我们机构连续22例患者接受了罗斯手术。手术时患者的平均年龄为40.4±10.2岁,大多数患者没有合并症(12/22)。最常见的手术指征是主动脉瓣狭窄(13/22),其次是主动脉瓣狭窄合并主动脉瓣关闭不全(7/22)。无死亡病例。术后,没有患者需要输血或因出血而再次手术探查。所有患者平均在术后5.9±1.1天出院。出院前超声心动图显示,术前至术后平均主动脉压力阶差显著降低(49±20mmHg对4±1mmHg;<0.01),且无主动脉瓣关闭不全,左、右心室功能无变化。

结论

我们证明,通过多学科教育和在带教监督下进行广泛的实践手术准备,可以安全地启动罗斯手术项目,获得优异的短期结果,且围手术期风险与传统外科主动脉瓣置换术相似。

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本文引用的文献

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The Ross Procedure: How I Teach It.罗斯手术:我是如何教授它的。
Ann Thorac Surg. 2018 May;105(5):1294-1298. doi: 10.1016/j.athoracsur.2018.01.048. Epub 2018 Feb 23.
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Rethinking the ross procedure in adults.重新思考成人的 Ross 手术。
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