Salvato Gerardo, Jenkinson Paul Mark, Sellitto Manuela, Crivelli Damiano, Crottini Francesco, Fazia Teresa, Squarza Silvia Amaryllis Claudia, Piano Mariangela, Sessa Maria, Gandola Martina, Fotopoulou Aikaterini, Bottini Gabriella
Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Cognitive Neuropsychology Centre, ASST "Grande Ospedale Metropolitano Niguarda", Milano, Italy.
Nat Commun. 2025 Jan 10;16(1):569. doi: 10.1038/s41467-025-55829-7.
Thermosensory signals may contribute to the sense of body ownership, but their role remains highly debated. We test this assumption within the framework of pathological body ownership, hypothesising that skin temperature and thermoception differ between right-hemisphere stroke patients with and without Disturbed Sensation of Ownership (DSO) for the contralesional plegic upper limb. Patients with DSO exhibit lower basal hand temperatures bilaterally and impaired perception of cold and warm stimuli. Lesion mapping reveals associations in the right Rolandic Operculum and Insula, with these regions linked to lower skin temperature located posterior to those associated with thermoception deficits. Disconnections in bilateral parietal regions are associated with lower hand temperature, while disconnections in a right-lateralized thalamus-parietal hub correlate with thermoception deficits. We discuss the theoretical implications of these findings in the context of the ongoing debate on the role of homeostatic signals in shaping a coherent sense of body ownership.
热感觉信号可能有助于身体所有权感，但它们的作用仍存在激烈争议。我们在病理性身体所有权的框架内检验这一假设，假设患有和未患有对患侧麻痹上肢的所有权感觉障碍（DSO）的右半球中风患者之间，皮肤温度和热感觉存在差异。患有DSO的患者双侧基础手部温度较低，对冷和热刺激的感知受损。病变映射显示右侧中央沟盖和脑岛存在关联，这些区域与位于热感觉缺陷相关区域后方的较低皮肤温度有关。双侧顶叶区域的连接中断与较低的手部温度相关，而右侧丘脑 - 顶叶枢纽的连接中断与热感觉缺陷相关。我们在关于稳态信号在塑造连贯身体所有权感中的作用的持续辩论背景下，讨论这些发现的理论意义。
