Elliott Christopher S, Huynh Hien-Khanh, Shem Kazuko
Stanford University Medical Center, Department of Urology, Stanford, CA, USA.
Santa Clara Valley Medical Center, Division of Urology, San Jose, CA, USA.
Spinal Cord. 2025 Mar;63(3):181-186. doi: 10.1038/s41393-024-01037-x. Epub 2025 Jan 10.
Retrospective review.
While most individuals with spinal cord injury (SCI) are expected to have 1-2 urinary tract infections (UTIs) per year, there is a subset with higher incidence. We evaluate our practice to characterize common causes of recurrent UTIs, hypothesizing that more frequent infections typically have addressable risk factors.
Tertiary urology clinic, San Jose, CA.
We reviewed patients with SCI referred to a tertiary urology clinic for evaluation and management of "recurrent UTIs" during the years 2015-2020. Following workup, the suspected cause of recurrent UTIs and number of post-specialty evaluation UTIs (patient reported) were noted.
Forty persons with SCI with a mean of 4.8 UTI treatments in the prior year comprised our cohort with most performing CIC (80%). After workup, 37/40 (92.5%) had a likely cause for their reported recurrent UTIs. In 16/40 (40%), careful questioning determined that the patient was not having UTIs based on guideline definitions. In those with confirmed recurrent UTIs, a bladder diary (62.5%) or urodynamic study (64%) was more likely to identify a cause compared to imaging (2.6%) or cystoscopy (8%). With a minimum 1-year follow-up, 90% of our population had a 50% or more reduction in UTI incidence, mostly using non-antibiotic strategies.
In a referral SCI population with a chief complaint of "recurrent UTIs", over a third were not having UTIs. In addition to detailed history, a bladder diary +/- urodynamics are most useful in finding the cause and improving UTI.
回顾性研究。
虽然大多数脊髓损伤(SCI)患者预计每年会发生1 - 2次尿路感染(UTI),但有一部分患者的发病率更高。我们评估我们的诊疗实践,以确定复发性UTI的常见原因,推测更频繁的感染通常存在可解决的风险因素。
加利福尼亚州圣何塞的三级泌尿外科诊所。
我们回顾了2015年至2020年期间因“复发性UTI”转诊至三级泌尿外科诊所进行评估和治疗的SCI患者。经过检查后,记录复发性UTI的疑似原因以及专科评估后UTI的发生次数(患者报告)。
40名SCI患者,上一年平均接受了4.8次UTI治疗,构成了我们的队列,其中大多数患者进行间歇性导尿(80%)。检查后,37/40(92.5%)的患者报告的复发性UTI可能有原因。在16/40(40%)的患者中,通过仔细询问确定患者根据指南定义并未发生UTI。在确诊为复发性UTI的患者中,膀胱日记(62.5%)或尿动力学检查(64%)比影像学检查(2.6%)或膀胱镜检查(8%)更有可能确定病因。经过至少1年的随访,我们队列中的90%患者UTI发病率降低了50%或更多,主要采用非抗生素策略。
在以“复发性UTI”为主诉的转诊SCI患者群体中,超过三分之一的患者并未发生UTI。除了详细的病史外,膀胱日记±尿动力学检查对于找出病因和改善UTI最为有用。