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Atezolizumab Plus Chemotherapy With or Without Bevacizumab in Advanced Biliary Tract Cancer: Clinical and Biomarker Data From the Randomized Phase II IMbrave151 Trial.阿替利珠单抗联合化疗加或不加贝伐单抗治疗晚期胆管癌：随机II期IMbrave151试验的临床和生物标志物数据
J Clin Oncol. 2025 Feb 10;43(5):545-557. doi: 10.1200/JCO.24.00337. Epub 2024 Oct 18.
3
The Search for Risk, Diagnostic, and Prognostic Biomarkers of Cholangiocarcinoma and Their Biological and Clinicopathologic Significance.胆管癌风险、诊断及预后生物标志物的探索及其生物学和临床病理意义
Am J Pathol. 2025 Mar;195(3):422-436. doi: 10.1016/j.ajpath.2024.06.013. Epub 2024 Aug 3.
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Durvalumab or placebo plus gemcitabine and cisplatin in participants with advanced biliary tract cancer (TOPAZ-1): updated overall survival from a randomised phase 3 study.度伐利尤单抗或安慰剂联合吉西他滨和顺铂治疗晚期胆道癌（TOPAZ-1）：一项随机 3 期研究的更新总生存期数据。
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Pembrolizumab in combination with gemcitabine and cisplatin compared with gemcitabine and cisplatin alone for patients with advanced biliary tract cancer (KEYNOTE-966): a randomised, double-blind, placebo-controlled, phase 3 trial.帕博利珠单抗联合吉西他滨和顺铂与单纯吉西他滨和顺铂治疗晚期胆道癌患者的比较（KEYNOTE-966）：一项随机、双盲、安慰剂对照、3 期临床试验。
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从其他肿瘤中学习：胆管癌的进展途径与挑战应对

Learning from Other Tumors: Pathways for Progress and Overcoming Challenges in Cholangiocarcinoma.

作者信息

Tesini Giulia, Braconi Chiara, Rimassa Lorenza, Macias Rocio I R

机构信息

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, 20072 Milan, Italy.

School of Cancer Sciences, University of Glasgow, Switchback Rd., Glasgow G61 1QH, UK.

出版信息

Cancers (Basel). 2025 Jan 6;17(1):156. doi: 10.3390/cancers17010156.

DOI:10.3390/cancers17010156
PMID:39796782
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11719734/
Abstract

Cholangiocarcinoma (CCA) is a group of complex and heterogeneous tumors originating from the epithelial cells of bile ducts that can occur in intrahepatic, perihilar, or distal localizations [...].

摘要

胆管癌（CCA）是一组起源于胆管上皮细胞的复杂且异质性肿瘤，可发生于肝内、肝门周围或远端部位[...]。