Chen Li, Wang Xiaojun, Wang Haijiao, Tang Yanhui, Luo Man, Chen Ming
The First Affiliated Hospital of Guangzhou University of Chinese Medicine, 510405, Guangzhou, China.
J Wound Care. 2025 Jan 2;34(1):5-8. doi: 10.12968/jowc.2023.0223.
Sweet syndrome (SS), which is characterised by fever and erythematous tender skin lesions, has been shown to be associated with lymphoma. However, there are limited reported experiences on the wound care of SS in patients with lymphoma. This case report presents the wound care of SS in a patient with anaplastic lymphoma kinase (ALK)-positive anaplastic large cell lymphoma (ALK+ALCL). A 42-year-old male was referred to the The First Affiliated Hospital of Guangzhou University of Chinese Medicine Hospital with redness and pain in the left shoulder and abdomen following chemotherapy for ALK+ALCL in early 2021. Physical examination found lesions in the abdomen and shoulder. The lesions were ruptured on day 5 and found to be composed of necrotic tissues. After debridement, the wounds were successively treated with silver ion antibacterial dressing, Mepilex Border Lite (Mölnlycke Health Care, Sweden), silver sulfadiazine gauze, Shengji ointment (a traditional Chinese therapy), UrgoTül (Urgo Medical, France), and fire needling therapy (another traditional Chinese therapy). At three months later, the wound in the abdomen was healed, but the shoulder wound was still unhealed. Based on the physiological manifestations and current treatment process, the patient was diagnosed with SS after multidisciplinary consultation. Prednisone tablets were then administered and the shoulder wound completely healed after two months.
Sweet综合征（SS）以发热和皮肤红斑性压痛性病变为特征，已被证明与淋巴瘤有关。然而，关于淋巴瘤患者SS伤口护理的报道经验有限。本病例报告介绍了一名间变性淋巴瘤激酶（ALK）阳性间变性大细胞淋巴瘤（ALK+ALCL）患者的SS伤口护理情况。一名42岁男性于2021年初因ALK+ALCL化疗后出现左肩和腹部发红疼痛，被转诊至广州中医药大学第一附属医院。体格检查发现腹部和肩部有病变。病变在第5天破裂，发现由坏死组织组成。清创后，伤口先后用银离子抗菌敷料、美皮康（瑞典墨尼克医疗用品公司）、磺胺嘧啶银纱布、生肌膏（一种中医疗法）、优格透（法国优格医疗公司）和火针疗法（另一种中医疗法）进行治疗。三个月后，腹部伤口愈合，但肩部伤口仍未愈合。根据生理表现和当前治疗过程，经多学科会诊后，该患者被诊断为SS。随后给予泼尼松片，两个月后肩部伤口完全愈合。
