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用于法医学评估作为腹腔镜胆囊切除术致命并发症的右肝动脉假性动脉瘤的体内成像与尸检结果之间的相关性

Correlation between in vivo imaging and post‑mortem autopsy findings for the medico-legal evaluation of a right hepatic artery pseudoaneurysm as a fatal complication of laparoscopic cholecystectomy.

作者信息

Pelletti Guido, Sech Maria, Montanari Nicola, Quaia Emilio, Garcea Domenico, Pelotti Susi

机构信息

Unit of Legal Medicine, Department of Medical and Surgical Sciences, University of Bologna, Via Irnerio 49, 40126, Bologna, Italy.

Department of Radiology, University of Padua, 35138, Padua, Italy.

出版信息

Forensic Sci Med Pathol. 2025 Jan 11. doi: 10.1007/s12024-024-00937-x.

DOI:10.1007/s12024-024-00937-x
PMID:39797962
Abstract

A 36-year-old woman diagnosed with complicated cholecystolithiasis underwent elective laparoscopic cholecystectomy (LC), then converted to open cholecystectomy because of a massive intraoperative bleeding. Hemostasis was performed with clipping and suturing the source of bleeding. In post-operative period, the patient suffered from persistent anemia associated with hemoperitoneum diagnosed through abdominal CT scanning, in absence of any sign of active bleeding. She died 16 days after the surgical procedure. Autopsy revealed the presence of 2 clips adjacent to the suture used for ligating the cystic artery and the presence of 3 surgical metal clips on the right hepatic artery, that should not be present in a routine cholecystectomy. The review of CT scans performed during the hospital stay revealed contrast extravasation from the right hepatic artery, near the 3 clips, allowing the post-mortem diagnosis of pseudoaneurysm (PA). The diagnosis of PA of right hepatic artery is typically made in living patients, through imaging, and autoptic identification is rarely obtained. The innovation of this report is to present an iconographic correlation between in vivo imaging and autopsy data, allowing for the tracing of the PA's origin to the wall weakening caused by the placement of 3 clips on the right hepatic artery, and having significant medico-legal implications.

摘要

一名36岁被诊断为复杂性胆囊结石的女性接受了择期腹腔镜胆囊切除术(LC),但因术中大量出血转为开腹胆囊切除术。通过夹闭和缝合出血源进行了止血。术后,患者出现持续性贫血,经腹部CT扫描诊断为腹腔积血,且无任何活动性出血迹象。她在手术后16天死亡。尸检发现,在用于结扎胆囊动脉的缝线附近有2个夹子,右肝动脉上有3个手术金属夹,而在常规胆囊切除术中不应出现这些夹子。对住院期间进行的CT扫描复查显示,在3个夹子附近的右肝动脉有造影剂外渗,从而在尸检时诊断为假性动脉瘤(PA)。右肝动脉假性动脉瘤的诊断通常在活体患者中通过影像学检查做出,很少通过尸检确定。本报告的创新之处在于展示了体内成像与尸检数据之间的图像相关性,从而能够追踪假性动脉瘤的起源是由于在右肝动脉放置3个夹子导致的血管壁薄弱,并且具有重大的法医学意义。

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本文引用的文献

1
Two cases of fatal insulin homicide resolved using combined immunohistochemistry and immunofluorescence techniques.运用免疫组织化学和免疫荧光技术联合检测解决了两例致命胰岛素杀人案。
Forensic Sci Med Pathol. 2024 Dec 26. doi: 10.1007/s12024-024-00921-5.
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A case of death after the severing three appendiceal arteries during appendectomy.一例阑尾切除术中三条阑尾动脉被切断后死亡的病例。
Forensic Sci Med Pathol. 2025 Mar;21(1):255-259. doi: 10.1007/s12024-024-00841-4. Epub 2024 Jul 13.
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经皮冠状动脉介入治疗期间的致命性冠状动脉穿孔:体内成像与尸检组织病理学之间建立相关性的法医学意义。
Forensic Sci Med Pathol. 2024 Dec;20(4):1543-1546. doi: 10.1007/s12024-023-00758-4. Epub 2023 Dec 10.
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