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本文引用的文献

1
Transcutaneous electrical acupoint stimulation alleviates cerebral ischemic injury through the TLR4/MyD88/NF-κ B pathway.经皮穴位电刺激通过TLR4/MyD88/NF-κB通路减轻脑缺血损伤。
Front Cell Neurosci. 2024 Jan 11;17:1343842. doi: 10.3389/fncel.2023.1343842. eCollection 2023.
2
Transcutaneous electrical acupoint stimulation attenuated neuroinflammation and oxidative stress by activating SIRT1-induced signaling pathway in MCAO/R rat models.经皮穴位电刺激通过激活 SIRT1 诱导的信号通路减轻 MCAO/R 大鼠模型中的神经炎症和氧化应激。
Exp Neurol. 2024 Mar;373:114658. doi: 10.1016/j.expneurol.2023.114658. Epub 2023 Dec 21.
3
Optimal Method of Electrical Stimulation for the Treatment of Upper Limb Dysfunction After Stroke: A Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials.中风后上肢功能障碍治疗的最佳电刺激方法:随机对照试验的系统评价和贝叶斯网络荟萃分析
Neuropsychiatr Dis Treat. 2021 Sep 15;17:2937-2954. doi: 10.2147/NDT.S332967. eCollection 2021.
4
A New Definition of Poststroke Spasticity and the Interference of Spasticity With Motor Recovery From Acute to Chronic Stages.一种新的卒中后痉挛定义以及痉挛对急性至慢性阶段运动恢复的干扰。
Neurorehabil Neural Repair. 2021 Jul;35(7):601-610. doi: 10.1177/15459683211011214. Epub 2021 May 12.
5
Prevalence and Risk Factors for Spasticity After Stroke: A Systematic Review and Meta-Analysis.中风后痉挛的患病率及危险因素:一项系统评价与荟萃分析。
Front Neurol. 2021 Jan 20;11:616097. doi: 10.3389/fneur.2020.616097. eCollection 2020.
6
An overview of fractional anisotropy as a reliable quantitative measurement for the corticospinal tract (CST) integrity in correlation with a Fugl-Meyer assessment in stroke rehabilitation.作为一种可靠的定量测量方法,分数各向异性用于评估皮质脊髓束(CST)完整性,并与中风康复中的Fugl-Meyer评估相关联的概述。
J Phys Ther Sci. 2021 Jan;33(1):75-83. doi: 10.1589/jpts.33.75. Epub 2021 Jan 5.
7
Intra- and inter-rater reliability of Fugl-Meyer Assessment of Upper Extremity in stroke.脑卒中患者上肢 Fugl-Meyer 评估的组内和组间信度。
J Rehabil Med. 2019 Oct 4;51(9):652-659. doi: 10.2340/16501977-2590.
8
When does spasticity in the upper limb develop after a first stroke? A nationwide observational study on 861 stroke patients.上肢痉挛在首次中风后何时出现?一项针对 861 例中风患者的全国性观察性研究。
J Clin Neurosci. 2019 Aug;66:144-148. doi: 10.1016/j.jocn.2019.04.034. Epub 2019 May 11.
9
Adjuvant treatments associated with botulinum toxin injection for managing spasticity: An overview of the literature.辅助治疗与肉毒毒素注射治疗痉挛:文献综述。
Ann Phys Rehabil Med. 2019 Jul;62(4):291-296. doi: 10.1016/j.rehab.2018.08.004. Epub 2018 Sep 13.
10
Clinical study of combined mirror and extracorporeal shock wave therapy on upper limb spasticity in poststroke patients.镜像疗法联合体外冲击波治疗对脑卒中后患者上肢痉挛的临床研究
Int J Rehabil Res. 2019 Mar;42(1):31-35. doi: 10.1097/MRR.0000000000000316.

经皮穴位电刺激治疗脑卒中后上肢痉挛:疗效与可行性——一项随机对照试验研究

Transcutaneous electrical acupoint stimulation for upper limb spasticity after stroke: effect and feasibility-a randomised pilot study.

作者信息

Wang Yuting, Zhang Lili, Yin Rui, Zhang Yuqing, Dai Zifeng, Wang Min, Song Jiali, Fan Xiaonong, Zhang Yanan, Yang Sha, Shen Yan, Yang Chen, Song Qian, Sun Sihan, Liu Jian

机构信息

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, Tianjin, China.

National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, Tianjin, China.

出版信息

BMJ Support Palliat Care. 2025 Feb 26;15(2):237-244. doi: 10.1136/spcare-2024-005174.

DOI:10.1136/spcare-2024-005174
PMID:39798944
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11874307/
Abstract

IMPORTANCE

Limb spasticity is a common issue among stroke patients. Transcutaneous electrical acupoint stimulation (TEAS) is recommended as an alternative therapy for managing upper limb spasticity after stroke; however, its potential effects and feasibility remain uncertain.

OBJECTIVE

To investigate the potential effects and feasibility of TEAS on motor function in patients with upper limb spasticity after stroke.

METHODS

This randomised controlled, double-blined pilot study was conducted in two phases. All the patients were randomly divided into two groups: the TEAS group and the sham TEAS group. The intervention period for both TEAS and sham TEAS was 6 weeks, with each session lasting 30 min and conducted thrice weekly. The outcomes measured were the Fugl-Meyer Assessment-Upper Extremity (FMA-UE) score, the effective improvement rate, the modified Ashworth Scale (MAS), the Wolf Motor Function Test (WMFT), the visual analogue scale (VAS), the Barthel index (BI) and the surface electromyography (sEMG).

RESULTS

All participants completed the course of therapy. Baseline characteristics were comparable across the two groups. Compared with the sham TEAS group, the TEAS group showed significant increases in FMA-UE score (P value=0.013), WMFT score (P value=0.001) and BI score (P value=0.008) at week 6. For integrated electromyogram (p=0.048) and root mean square of the biceps (p=0.033), lower scores were identified in the TEAS group compared with the sham TEAS group with a significant difference at week 6.

CONCLUSION

TEAS was acceptable and feasible in participants with upper limb spasticity after stroke. A pivotal study of this therapy is justified.

摘要

重要性

肢体痉挛是中风患者的常见问题。经皮穴位电刺激(TEAS)被推荐作为中风后上肢痉挛的替代治疗方法;然而,其潜在效果和可行性仍不确定。

目的

探讨经皮穴位电刺激(TEAS)对中风后上肢痉挛患者运动功能的潜在效果和可行性。

方法

这项随机对照双盲试验分两个阶段进行。所有患者随机分为两组:TEAS组和假TEAS组。TEAS组和假TEAS组的干预期均为6周,每次治疗持续30分钟,每周进行三次。测量的结果包括Fugl-Meyer上肢评估(FMA-UE)评分、有效改善率、改良Ashworth量表(MAS)、Wolf运动功能测试(WMFT)、视觉模拟量表(VAS)、Barthel指数(BI)和表面肌电图(sEMG)。

结果

所有参与者均完成了治疗疗程。两组的基线特征具有可比性。与假TEAS组相比,TEAS组在第6周时FMA-UE评分(P值=0.013)、WMFT评分(P值=0.001)和BI评分(P值=0.008)显著增加。对于积分肌电图(p=0.048)和肱二头肌均方根(p=0.033),TEAS组与假TEAS组相比得分更低,在第6周时有显著差异。

结论

经皮穴位电刺激(TEAS)对中风后上肢痉挛患者是可接受且可行的。对该疗法进行关键研究是合理的。