人巨细胞病毒和严重急性呼吸综合征冠状病毒2在一名晚期艾滋病患者肺组织中的不同嗜性
Distinct tropisms of HCMV and SARS-CoV-2 in lung tissue of a patient with advanced HIV disease.
作者信息
Xu Jingjing, Yang Bo, Zheng Ye, Yang Yuexiang, Luo Min-Hua, Ling Yun, Fan Xiaohong, Cheng Han
机构信息
Shanghai Public Health Clinical Center, Fudan University, Shanghai 201508, China.
State Key Laboratory of Virology, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan 430071, China.
出版信息
Virol Sin. 2025 Feb;40(1):141-143. doi: 10.1016/j.virs.2025.01.001. Epub 2025 Jan 10.
• This report presents a rare case of co-infection with SARS-CoV-2 and HCMV in a patient with severe AIDS. • Despite suppression of SARS-CoV-2, HCMV pneumonia contributed to the patient's death. • Distinct HCMV/SARS-CoV-2 lung infection patterns suggest synergistic damage from co-infection.
• 本报告介绍了一例重症艾滋病患者同时感染新型冠状病毒2型（SARS-CoV-2）和人巨细胞病毒（HCMV）的罕见病例。• 尽管SARS-CoV-2得到抑制，但HCMV肺炎导致了患者死亡。• 不同的HCMV/SARS-CoV-2肺部感染模式提示合并感染存在协同损伤。
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